The Stanford-South Africa Pharmacogenomics Course

The Stanford-South Africa Biomedical Informatics (SSABMI) Training Program expands teaching, training, and research opportunities for individuals interested in the application of informatics technologies to problems in biomedical research. The program is a partnership between the University of the Western Cape, the University of Cape Town, the National Institute of Communicable Diseases, and Stanford University. Please see the Stanford-South Africa Biomedical Informatics Program web site for more details.

As part of this program, two members of the PharmGKB team -- Russ B. Altman, M.D., Ph.D. and Caroline Thorn, Ph.D. -- presented a course on Pharmacogenetics and Pharmacogenomics. A list of the topics covered is given below, with downloadable versions of the slides used for each talk.

The following are PDF files:

By Russ B. Altman, MD, PhD

• Introduction to Pharmacogenomics
• Approaches to Pharmacogenomic Studies
• Pathways of Drug Metabolism and Action
• Drug Interactions and Adverse Drug Reactions
• Drug Discovery and Validation
• Clinical Setting of Pharmacogenomics
• Pharmacology: Basic Principles
• Building the PharmGKB: A Web Tool for Pharmacogenomics
• Technical Issues for PharmGKB
• Ethical Issues for Pharmacogenomics
• The Published Literature as a Data Source for PGx

By Caroline Thorn, PhD

• Human Polymorphisms
• Classical Pharmacogenetics
• Non-classical Pharmacogenetics and Pharmacogenomics
• Methods for Genomic Variation Discovery & Genotyping
• Methods for Molecular, Cellular and Clinical Phenotypes & Data Exchange
• Cancer Pharmacogenomics
• Pharmacogenomics and Cardiovascular Health
• Pharmacogenomics and HIV

By Pui-Yan Kwok, MD, PhD

• Technologies for Genetic Analysis of Complex Traits

Get the DVD!

A set of DVDs of the live presentations of the Pharmacogenomics course is also available.