SLC22A1-ABCB1 haplotype profiles predict imatinib pharmacokinetics in Asian patients with chronic myeloid leukemia by Singh Onkar, Chan Jason Yongsheng, Lin Keegan, Heng Charles Chuah Thuan, Chowbay Balram in PloS one (2012). PubMed

Abstract

This study aimed to explore the influence of SLC22A1, PXR, ABCG2, ABCB1 and CYP3A5 3 genetic polymorphisms on imatinib mesylate (IM) pharmacokinetics in Asian patients with chronic myeloid leukemia (CML).

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