The relationship between clinical pharmacokinetics of aripiprazole and CYP2D6 genetic polymorphism: effects of CYP enzyme inhibition by coadministration of paroxetine or fluvoxamine by Azuma Junichi, Hasunuma Tomoko, Kubo Masanori, Miyatake Masaya, Koue Toshiko, Higashi Koushi, Fujiwara Tsutomu, Kitahara Sachiko, Katano Tamiki, Hara Sumiko in European journal of clinical pharmacology (2012). PubMed

Abstract

To investigate the effects of coadministration of paroxetine or fluvoxamine on the pharmacokinetics of aripiprazole in healthy adult Japanese with different CYP2D6 genotypes.

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