Role of organic cation transporter 3 (SLC22A3) and its missense variants in the pharmacologic action of metformin by Chen Ligong, Pawlikowski Bradley, Schlessinger Avner, More Swati S, Stryke Doug, Johns Susan J, Portman Michael A, Chen Eugene, Ferrin Thomas E, Sali Andrej, Giacomini Kathleen M in Pharmacogenetics and genomics (2010). PubMed

Abstract

The goals of this study were to determine the role of organic cation transporter 3 (OCT3) in the pharmacological action of metformin and to identify and functionally characterize genetic variants of OCT3 with respect to the uptake of metformin and monoamines.

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