Variants of DENND1B associated with asthma in children by Sleiman Patrick M A, Flory James, Imielinski Marcin, Bradfield Jonathan P, Annaiah Kiran, Willis-Owen Saffron A G, Wang Kai, Rafaels Nicholas M, Michel Sven, Bonnelykke Klaus, Zhang Haitao, Kim Cecilia E, Frackelton Edward C, Glessner Joseph T, Hou Cuiping, Otieno F George, Santa Erin, Thomas Kelly, Smith Ryan M, Glaberson Wendy R, Garris Maria, Chiavacci Rosetta M, Beaty Terri H, Ruczinski Ingo, Orange Jordan M, Allen Julian, Spergel Jonathan M, Grundmeier Robert, Mathias Rasika A, Christie Jason D, von Mutius Erika, Cookson William O C, Kabesch Michael, Moffatt Miriam F, Grunstein Michael M, Barnes Kathleen C, Devoto Marcella, Magnusson Mark, Li Hongzhe, Grant Struan F A, Bisgaard Hans, Hakonarson Hakon in The New England journal of medicine (2010). PubMed

Abstract

Asthma is a complex disease that has genetic and environmental causes. The genetic factors associated with susceptibility to asthma remain largely unknown.

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