Association of APOE polymorphism with chronic kidney disease in a nationally representative sample: a Third National Health and Nutrition Examination Survey (NHANES III) Genetic Study by Chu Audrey Y, Parekh Rulan S, Astor Brad C, Coresh Josef, Berthier-Schaad Yvette, Smith Michael W, Shuldiner Alan R, Kao Wen Hong L in BMC medical genetics (2009). PubMed

Abstract

Apolipoprotein E polymorphisms (APOE) have been associated with lowered glomerular filtration rate (GFR) and chronic kidney disease (CKD) with e2 allele conferring risk and e4 providing protection. However, few data are available in non-European ethnic groups or in a population-based cohort.

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