CSF biomarkers and incipient Alzheimer disease in patients with mild cognitive impairment by Mattsson Niklas, Zetterberg Henrik, Hansson Oskar, Andreasen Niels, Parnetti Lucilla, Jonsson Michael, Herukka Sanna-Kaisa, van der Flier Wiesje M, Blankenstein Marinus A, Ewers Michael, Rich Kenneth, Kaiser Elmar, Verbeek Marcel, Tsolaki Magda, Mulugeta Ezra, Rosén Erik, Aarsland Dag, Visser Pieter Jelle, Schröder Johannes, Marcusson Jan, de Leon Mony, Hampel Harald, Scheltens Philip, Pirttilä Tuula, Wallin Anders, Jönhagen Maria Eriksdotter, Minthon Lennart, Winblad Bengt, Blennow Kaj in JAMA : the journal of the American Medical Association (2009). PubMed

Abstract

Small single-center studies have shown that cerebrospinal fluid (CSF) biomarkers may be useful to identify incipient Alzheimer disease (AD) in patients with mild cognitive impairment (MCI), but large-scale multicenter studies have not been conducted.

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