Multidrug resistance-related protein 2 genotype of the donor affects kidney graft function by Grisk Olaf, Steinbach Antje C, Ciecholewski Sabine, Schlüter Torsten, Klöting Ingrid, Schmidt Helmut, Dazert Eike, Schaeffeler Elke, Steil Leif, Gauer Stefan, Jedlitschky Gabriele, Schwab Matthias, Geisslinger Gerd, Hauser Ingeborg A, Völker Uwe, Kroemer Heyo K, Rettig Rainer in Pharmacogenetics and genomics (2009). PubMed

Abstract

We tested the effect of kidney-specific multidrug resistance-related protein (MRP2, ABCC2) deficiency on renal organic solute disposition as well as on renal protein and gene expression. Furthermore, we investigated whether a particular kidney donor ABCC2 genotype is associated with delayed graft function in patients.

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