The 18-kDa translocator protein, formerly known as the peripheral-type benzodiazepine receptor, confers proapoptotic and antineoplastic effects in a human colorectal cancer cell line by Shoukrun Rami, Veenman Leo, Shandalov Yulia, Leschiner Svetlana, Spanier Ilana, Karry Rachel, Katz Yeshayahu, Weisinger Gary, Weizman Abraham, Gavish Moshe in Pharmacogenetics and genomics (2008). PubMed

Abstract

The involvement of the 18-kDa translocator protein (TSPO), formerly known as the peripheral-type benzodiazepine receptor, in apoptosis regulation of HT29 colorectal cancer cells was studied in-vitro. In-vivo TSPO involvement in tumor growth of HT29 cells xenografted into SCID mice was studied.

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