Obesity associated genetic variation in FTO is associated with diminished satiety by Wardle Jane, Carnell Susan, Haworth Claire M A, Farooqi I Sadaf, O'Rahilly Stephen, Plomin Robert in The Journal of clinical endocrinology and metabolism (2008). PubMed

Abstract

Polymorphisms within the FTO gene have consistently been associated with obesity across multiple populations. However, to date, it is not known whether the association between genetic variation in FTO and obesity is mediated through effects on energy intake or energy expenditure.

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