HLA-B*5701 screening for hypersensitivity to abacavir by Mallal Simon, Phillips Elizabeth, Carosi Giampiero, Molina Jean-Michel, Workman Cassy, Tomazic Janez, J├Ągel-Guedes Eva, Rugina Sorin, Kozyrev Oleg, Cid Juan Flores, Hay Phillip, Nolan David, Hughes Sara, Hughes Arlene, Ryan Susanna, Fitch Nicholas, Thorborn Daren, Benbow Alastair, PREDICT-1 Study Team in The New England journal of medicine (2008). PubMed

Abstract

Hypersensitivity reaction to abacavir is strongly associated with the presence of the HLA-B*5701 allele. This study was designed to establish the effectiveness of prospective HLA-B*5701 screening to prevent the hypersensitivity reaction to abacavir.

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