Dopamine agonists and the risk of cardiac-valve regurgitation by Schade René, Andersohn Frank, Suissa Samy, Haverkamp Wilhelm, Garbe Edeltraut in The New England journal of medicine (2007). PubMed

Abstract

Case reports and echocardiographic studies suggest that the ergot-derived dopamine agonists pergolide and cabergoline, used in the treatment of Parkinson's disease and the restless legs syndrome, may increase the risk of cardiac-valve regurgitation.

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