High risk for hyperlipidemia and the metabolic syndrome after an episode of hypertriglyceridemia during 13-cis retinoic acid therapy for acne: a pharmacogenetic study by Rodondi Nicolas, Darioli Roger, Ramelet Albert-Adrien, Hohl Daniel, Lenain Vincent, Perdrix Jean, Wietlisbach Vincent, Riesen Walter F, Walther Thomas, Medinger Laurent, Nicod Pascal, Desvergne BĂ©atrice, Mooser Vincent in Annals of internal medicine (2002). PubMed

Abstract

Administration of 13-cis retinoic acid (isotretinoin) for acne is occasionally accompanied by hyperlipidemia. It is not known why some persons develop this side effect.

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