CYP2D6 and CYP2C19 genotype-based dose recommendations for antidepressants: a first step towards subpopulation-specific dosages by Kirchheiner J, Brøsen K, Dahl M L, Gram L F, Kasper S, Roots I, Sjöqvist F, Spina E, Brockmöller J in Acta psychiatrica Scandinavica (2001). PubMed

Abstract

This review aimed to provide distinct dose recommendations for antidepressants based on the genotypes of cytochrome P450 enzymes CYP2D6 and CYP2C19. This approach may be a useful complementation to clinical monitoring and therapeutic drug monitoring.

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