In vivo and in vitro induction of human cytochrome P4503A4 by dexamethasone by McCune J S, Hawke R L, LeCluyse E L, Gillenwater H H, Hamilton G, Ritchie J, Lindley C in Clinical pharmacology and therapeutics (2000). PubMed

Abstract

The aims of these experiments were to determine the effect of a therapeutic regimen of dexamethasone on cytochrome P4503A4 (CYP3A4) activity in healthy volunteers; and the concentration-effect relationship between dexamethasone and CYP3A4 activity in primary human hepatocyte cultures.

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