ATPase, Cu++ transporting, beta polypeptide
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This is a non-comprehensive list of genetic tests with pharmacogenetics relevance, typically submitted by the manufacturer and manually curated by PharmGKB. The information listed is provided for educational purposes only and does not constitute an endorsement of any listed test or manufacturer.
A more complete listing of genetic tests is found at the Genetic Testing Registry (GTR).
|PGx Test||Variants Assayed||Related Drugs?|
|Alternate Names:||Wilson disease; copper pump 2; copper-transporting ATPase 2|
|Alternate Symbols: ||None|
|PharmGKB Accession Id:||PA73|
|Cytogenetic Location:||chr13 : q14.3 - q14.3|
|GP mRNA Boundary†:||chr13 : 52506805 - 52585630|
|GP Gene Boundary†:||chr13 : 52503805 - 52595630|
PharmGKB Curated Pathways
Pathways created internally by PharmGKB based primarily on literature evidence.
Platinum Pathway, Pharmacokinetics/Pharmacodynamics
Representation of the candidate genes involved in the metabolism of platinum containing drugs.
Links to non-PharmGKB pathways.
PharmGKB contains no links to external pathways for this gene. To report a pathway, click here.
Publications related to ATP7B: 2
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- DG Dosing Guideline information is available
- DL Drug Label information is available
- CA High-level Clinical Annotation is available
- VA Variant Annotation is available
- VIP VIP information is available
- PW Pathway is available
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||Resistance gene expression determines the in vitro chemosensitivity of non-small cell lung cancer (NSCLC). BMC cancer. 2009. Glaysher Sharon, et al.|
||Genetic polymorphisms of copper- and platinum drug-efflux transporters ATP7A and ATP7B in Japanese cancer patients. Drug metabolism and pharmacokinetics. 2009. Fukushima-Uesaka Hiromi, et al.|