Gene:
CKS1B
CDC28 protein kinase regulatory subunit 1B

PharmGKB contains no dosing guidelines for this gene. To report known dosing guidelines, or if you are interested in developing guidelines, click here.

PharmGKB contains no drug labels with pharmacogenomic information for this gene. To report a drug label with PGx, click here.

PharmGKB contains no clinical annotations for this gene. To report clinical variants, click here.

PharmGKB contains no genetic tests for this gene. To report genetic tests, click here.

Overview

Alternate Names:  CDC2-associated protein CKS1; CDC28 protein kinase 1; CDC28 protein kinase 1B; CKS-1; NB4 apoptosis/differentiation related protein; OTTHUMP00000035541; PNAS-143; cell division control protein CKS1; cyclin-dependent kinases regulatory subunit 1
Alternate Symbols:  CKS1; PNAS-16; PNAS-18; ckshs1
PharmGKB Accession Id: PA38791

Details

Cytogenetic Location: chr1 : q21.3 - q21.3
GP mRNA Boundary: chr1 : 154947118 - 154951725
GP Gene Boundary: chr1 : 154937118 - 154954725
Strand: plus
Product Name: No data available
The mRNA boundaries are calculated using the gene's default feature set from NCBI, mapped onto the UCSC Golden Path. PharmGKB sets gene boundaries by expanding the mRNA boundaries by no less than 10,000 bases upstream (5') and 3,000 bases downstream (3') to allow for potential regulatory regions.

PharmGKB Curated Pathways

Pathways created internally by PharmGKB based primarily on literature evidence.

PharmGKB contains no curated pathways for this gene. If you would like to volunteer to work on a pathway, please let us know.

External Pathways

Links to non-PharmGKB pathways.

  1. FOXM1 transcription factor network - (Pathway Interaction Database NCI-Nature Curated)
  2. regulation of p27 phosphorylation during cell cycle progression - (BioCarta via Pathway Interaction Database)
  3. SCF(Skp2)-mediated degradation of p27/p21 - (Reactome via Pathway Interaction Database)

LinkOuts

Entrez Gene:
1163
OMIM:
116900
UCSC Genome Browser:
NM_001826
RefSeq RNA:
NM_001826
NR_024163
RefSeq Protein:
NP_001817
MutDB:
CKS1B
HuGE:
CKS1B
Comparative Toxicogenomics Database:
1163
ModBase:
P61024
HumanCyc Gene:
HS10628
HS11295
HGNC:
19083

Common Searches

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