Gene:
ZBTB16
zinc finger and BTB domain containing 16

PharmGKB contains no dosing guidelines for this . To report known genotype-based dosing guidelines, or if you are interested in developing guidelines, click here.

PharmGKB has no annotated drug labels with pharmacogenomic information for this . If you know of a drug label with PGx, send us a message.

PharmGKB contains no Clinical Variants that meet the highest level of criteria.

Disclaimer: The PharmGKB's clinical annotations reflect expert consensus based on clinical evidence and peer-reviewed literature available at the time they are written and are intended only to assist clinicians in decision-making and to identify questions for further research. New evidence may have emerged since the time an annotation was submitted to the PharmGKB. The annotations are limited in scope and are not applicable to interventions or diseases that are not specifically identified.

The annotations do not account for individual variations among patients, and cannot be considered inclusive of all proper methods of care or exclusive of other treatments. It remains the responsibility of the health-care provider to determine the best course of treatment for a patient. Adherence to any guideline is voluntary, with the ultimate determination regarding its application to be made solely by the clinician and the patient. PharmGKB assumes no responsibility for any injury or damage to persons or property arising out of or related to any use of the PharmGKB clinical annotations, or for any errors or omissions.

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This is a non-comprehensive list of genetic tests with pharmacogenetics relevance, typically submitted by the manufacturer and manually curated by PharmGKB. The information listed is provided for educational purposes only and does not constitute an endorsement of any listed test or manufacturer.

A more complete listing of genetic tests is found at the Genetic Testing Registry (GTR).

PGx Test Variants Assayed Related Drugs?

Overview

Alternate Names:  None
Alternate Symbols:  PLZF
PharmGKB Accession Id: PA37517

Details

Cytogenetic Location: chr11 : q23.1 - q23.2
GP mRNA Boundary: chr11 : 113930431 - 114121398
GP Gene Boundary: chr11 : 113920431 - 114124398
Strand: plus
The mRNA boundaries are calculated using the gene's default feature set from NCBI, mapped onto the UCSC Golden Path. PharmGKB sets gene boundaries by expanding the mRNA boundaries by no less than 10,000 bases upstream (5') and 3,000 bases downstream (3') to allow for potential regulatory regions.

PharmGKB Curated Pathways

Pathways created internally by PharmGKB based primarily on literature evidence.

PharmGKB contains no curated pathways for this gene. If you would like to volunteer to work on a pathway, please let us know.

External Pathways

Links to non-PharmGKB pathways.

  1. map kinase inactivation of smrt corepressor - (BioCarta via Pathway Interaction Database)

Publications related to ZBTB16: 2

No Dosing Guideline available No Drug Label available No Clinical Annotation available No Variant Annotation available No VIP available No VIP available
Emerging concepts of regulation of angiotensin II receptors: new players and targets for traditional receptors. Arteriosclerosis, thrombosis, and vascular biology. 2007. Mogi Masaki, et al. PubMed
No Dosing Guideline available No Drug Label available No Clinical Annotation available No Variant Annotation available No VIP available No VIP available
Genomewide identification of prednisolone-responsive genes in acute lymphoblastic leukemia cells. Blood. 2007. Tissing Wim J E, et al. PubMed

LinkOuts

Entrez Gene:
7704
OMIM:
176797
612447
UCSC Genome Browser:
NM_006006
RefSeq RNA:
NM_001018011
NM_006006
RefSeq Protein:
NP_001018011
NP_005997
RefSeq DNA:
AC_000054
AC_000143
NC_000011
NG_012140
NT_033899
NW_001838042
NW_925173
UniProtKB:
ZBT16_HUMAN (Q05516)
Ensembl:
ENSG00000109906
GenAtlas:
ZBTB16
GeneCard:
ZBTB16
MutDB:
ZBTB16
ALFRED:
LO002003F
HuGE:
ZBTB16
Comparative Toxicogenomics Database:
7704
ModBase:
Q05516
HumanCyc Gene:
HS03266
HGNC:
12930

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