Gene:
SLC25A4
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4

PharmGKB contains no dosing guidelines for this . To report known genotype-based dosing guidelines, or if you are interested in developing guidelines, click here.

PharmGKB contains no drug labels with pharmacogenomic information for this . To report a drug label with PGx, click here.

Disclaimer: The PharmGKB's clinical annotations reflect expert consensus based on clinical evidence and peer-reviewed literature available at the time they are written and are intended only to assist clinicians in decision-making and to identify questions for further research. New evidence may have emerged since the time an annotation was submitted to the PharmGKB. The annotations are limited in scope and are not applicable to interventions or diseases that are not specifically identified.

The annotations do not account for individual variations among patients, and cannot be considered inclusive of all proper methods of care or exclusive of other treatments. It remains the responsibility of the health-care provider to determine the best course of treatment for a patient. Adherence to any guideline is voluntary, with the ultimate determination regarding its application to be made solely by the clinician and the patient. PharmGKB assumes no responsibility for any injury or damage to persons or property arising out of or related to any use of the PharmGKB clinical annotations, or for any errors or omissions.

? = Mouse-over for quick help

This is a non-comprehensive list of genetic tests with pharmacogenetics relevance, typically submitted by the manufacturer and manually curated by PharmGKB. The information listed is provided for educational purposes only and does not constitute an endorsement of any listed test or manufacturer.

A more complete listing of genetic tests is found at the Genetic Testing Registry (GTR).

PGx Test Variants Assayed Related Drugs?

Overview

Alternate Names:  None
Alternate Symbols:  T1
PharmGKB Accession Id: PA35866

Details

Cytogenetic Location: chr4 : q35.1 - q35.1
GP mRNA Boundary: chr4 : 186064417 - 186071538
GP Gene Boundary: chr4 : 186054417 - 186074538
Strand: plus
The mRNA boundaries are calculated using the gene's default feature set from NCBI, mapped onto the UCSC Golden Path. PharmGKB sets gene boundaries by expanding the mRNA boundaries by no less than 10,000 bases upstream (5') and 3,000 bases downstream (3') to allow for potential regulatory regions.

PharmGKB Curated Pathways

Pathways created internally by PharmGKB based primarily on literature evidence.

External Pathways

Links to non-PharmGKB pathways.

PharmGKB contains no links to external pathways for this gene. To report a pathway, click here.

LinkOuts

Entrez Gene:
291
OMIM:
103220
157640
192600
609283
UCSC Genome Browser:
NM_001151
RefSeq RNA:
NM_001151
RefSeq Protein:
NP_001142
RefSeq DNA:
AC_000047
AC_000136
NC_000004
NG_013001
NT_016354
NW_001838921
NW_922217
UniProtKB:
ADT1_HUMAN (P12235)
Ensembl:
ENSG00000151729
GenAtlas:
SLC25A4
GeneCard:
SLC25A4
MutDB:
SLC25A4
ALFRED:
LO014048R
HuGE:
SLC25A4
Comparative Toxicogenomics Database:
291
ModBase:
P12235
HumanCyc Gene:
HS07767
HGNC:
10990

Common Searches