Gene:
SFTPB
surfactant protein B

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Disclaimer: The PharmGKB's clinical annotations reflect expert consensus based on clinical evidence and peer-reviewed literature available at the time they are written and are intended only to assist clinicians in decision-making and to identify questions for further research. New evidence may have emerged since the time an annotation was submitted to the PharmGKB. The annotations are limited in scope and are not applicable to interventions or diseases that are not specifically identified.

The annotations do not account for individual variations among patients, and cannot be considered inclusive of all proper methods of care or exclusive of other treatments. It remains the responsibility of the health-care provider to determine the best course of treatment for a patient. Adherence to any guideline is voluntary, with the ultimate determination regarding its application to be made solely by the clinician and the patient. PharmGKB assumes no responsibility for any injury or damage to persons or property arising out of or related to any use of the PharmGKB clinical annotations, or for any errors or omissions.

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This is a non-comprehensive list of genetic tests with pharmacogenetics relevance, typically submitted by the manufacturer and manually curated by PharmGKB. The information listed is provided for educational purposes only and does not constitute an endorsement of any listed test or manufacturer.

A more complete listing of genetic tests is found at the Genetic Testing Registry (GTR).

PGx Test Variants Assayed Related Drugs?

Overview

Alternate Names:  None
Alternate Symbols:  SP-B
PharmGKB Accession Id: PA35713

Details

Cytogenetic Location: chr2 : p12 - p11.2
GP mRNA Boundary: chr2 : 85884440 - 85895864
GP Gene Boundary: chr2 : 85881440 - 85905864
Strand: minus
The mRNA boundaries are calculated using the gene's default feature set from NCBI, mapped onto the UCSC Golden Path. PharmGKB sets gene boundaries by expanding the mRNA boundaries by no less than 10,000 bases upstream (5') and 3,000 bases downstream (3') to allow for potential regulatory regions.

LinkOuts

Entrez Gene:
6439
OMIM:
178640
265120
UCSC Genome Browser:
NM_000542
RefSeq RNA:
NM_000542
NM_198843
RefSeq Protein:
NP_000533
NP_942140
RefSeq DNA:
AC_000045
AC_000134
NC_000002
NG_016967
NT_022184
NW_001838769
NW_927719
UniProtKB:
PSPB_HUMAN (P07988)
Ensembl:
ENSG00000168878
GenAtlas:
SFTPB
GeneCard:
SFTPB
MutDB:
SFTPB
ALFRED:
LO061966C
HuGE:
SFTPB
Comparative Toxicogenomics Database:
6439
ModBase:
P07988
HumanCyc Gene:
HS09842
HGNC:
10801

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