PharmGKB contains no dosing guidelines for this gene. To report known dosing guidelines, or if you are interested in developing guidelines, click here.
PharmGKB contains no drug labels with pharmacogenomic information for this gene. To report a drug label with PGx, click here.
PharmGKB contains no clinical annotations for this gene. To report clinical variants, click here.
PharmGKB contains no genetic tests for this gene. To report genetic tests, click here.
The table below contains information about pharmacogenomic variants on PharmGKB. Please follow the link in the "Variant" column for more information about a particular variant. Each link in the "Variant" column leads to the corresponding PharmGKB Variant Page. The Variant Page contains summary data, including PharmGKB manually curated information about variant-drug pairs based on individual PubMed publications. The PMIDs for these PubMed publications can be found on the Variant Page.
The tags in the first column of the table indicate what type of information can be found on the corresponding Variant Page.
Links in the "Drugs" column lead to PharmGKB Drug Pages.
|
Variant?
(build 132) |
Alternate Names ? | Drugs ? | Alleles ? | Function ? |
Amino Acid?
Translation |
|
|---|---|---|---|---|---|---|
| rs1801030 | SULT1A1*3, SULT1A1:667A>G, SULT1A1:Met223Val, c.433G>A, c.667G>A, g.28557485C>T, p.Val145Met, p.Val223Met | C > T | Missense | Val223Met | ||
| rs3760091 | SULT1A1: -624G>C, c.-36+452G>A, c.-36+452G>C, c.-5+452G>A, c.139-2402G>A, c.139-2402G>C, g.28560800C>G, g.28560800C>T | C/G/T | Not Available | |||
| rs750155 | SULT1A1: -396 G>A, c.-197G>A, c.-35-361G>A, c.-396G>A, c.-4-392G>A, c.139-2174G>A, g.28560572C>T | C/T | Not Available | |||
| rs9282861 | SULT1A1*2, SULT1A1:638G>A:SULT1A1:Arg213His, c.404G>A, c.638G>A, g.28557514C>T, p.Arg135His, p.Arg213His | C > T | Missense | Arg135His |
Overview
| Alternate Names: | OTTHUMP00000162569; P-PST 1; aryl sulfotransferase; aryl sulfotransferase 1; phenol sulfotransferase 1; phenol-preferring phenol sulfotransferase1; phenol-sulfating phenol sulfotransferase; phenol-sulfating phenol sulfotransferase 1; sulfotransferase 1A1; sulfotransferase family 1A, phenol-preferring, member 1; thermostable phenol sulfotransferase; thermostable phenol sulfotransferase1; ts-PST |
|---|---|
| Alternate Symbols: | HAST1/HAST2; MGC131921; MGC5163; P-PST; PST; ST1A1; ST1A3; STP; STP1; TSPST1 |
| Haplotypes: | SULT1A1*1; SULT1A1*2; SULT1A1*3; SULT1A1*5 |
| PharmGKB Accession Id: | PA343 |
Details
| Cytogenetic Location: | chr16 : p11.2 - p11.2 |
|---|---|
| GP mRNA Boundary†: | chr16 : 28616913 - 28634866 |
| GP Gene Boundary†: | chr16 : 28613913 - 28644866 |
| Strand: | minus |
| Product Name: | aryl sulfotransferase, phenol-preferring phenol sulfotransferase1, phenol-sulfating phenol sulfotransferase, sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1, sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 isoform a, sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 isoform b, thermostable phenol sulfotransferase1 |
All alleles are displayed on the positive chromosomal strand.
PharmGKB Curated Pathways
Pathways created internally by PharmGKB based primarily on literature evidence.
-
Aromatase Inhibitor Pathway (Multiple Tissues), Pharmacodynamics
Diagrammatic representation of the synthesis of estrogen in post-menopausal women and its blockade by aromatase inhibitors.
-
Estrogen Metabolism Pathway
Estrogen metabolism in the liver.
External Pathways
Links to non-PharmGKB pathways.
Datasets
Downloads
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LinkOuts
- UniProtKB:
- ST1A1_HUMAN (P50225)
- Ensembl:
- ENSG00000196502
- GenAtlas:
- SULT1A1
- GeneCard:
- GC16M028616 (6817)
- SOURCE:
- SULT1A1
- MutDB:
- SULT1A1
Common Searches
Non-Curated Publications
A list of non-curated publications that mention this gene is available.