Gene:
PDE1A
phosphodiesterase 1A, calmodulin-dependent

PharmGKB contains no dosing guidelines for this gene. To report known dosing guidelines, or if you are interested in developing guidelines, click here.

PharmGKB contains no drug labels with pharmacogenomic information for this gene. To report a drug label with PGx, click here.

PharmGKB contains no clinical annotations for this gene. To report clinical variants, click here.

PharmGKB contains no genetic tests for this gene. To report genetic tests, click here.

Overview

Alternate Names:  3',5' cyclic nucleotide phosphodiesterase; 61 kDa Cam-PDE; Human 3',5' cyclic nucleotide phosphodiesterase (HSPDE1A3A); OTTHUMP00000163419; OTTHUMP00000205289; OTTHUMP00000205290; Phosphodiesterase-1A; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A; calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase; calmodulin-dependent phosphodiesterase; cam-PDE 1A; hCam-1; phosphodiesterase-1A
Alternate Symbols:  HCAM1; HSPDE1A; MGC26303
PharmGKB Accession Id: PA33122

Details

Cytogenetic Location: chr2 : q32.1 - q32.1
GP mRNA Boundary: chr2 : 183007183 - 183387465
GP Gene Boundary: chr2 : 183004183 - 183397465
Strand: minus
Product Name: No data available
The mRNA boundaries are calculated using the gene's default feature set from NCBI, mapped onto the UCSC Golden Path. PharmGKB sets gene boundaries by expanding the mRNA boundaries by no less than 10,000 bases upstream (5') and 3,000 bases downstream (3') to allow for potential regulatory regions.

Publications related to PDE1A: 2

No Dosing Guideline available No Drug Label available No Clinical Annotation available No Variant Annotation available No VIP available No VIP available
Pharmacogenetic investigation of response to duloxetine treatment in generalized anxiety disorder. The pharmacogenomics journal. 2012. Perlis R H, et al. [Article:22249355@PubMed]
No Dosing Guideline available No Drug Label available No Clinical Annotation available No Variant Annotation available No VIP available No VIP available
Phosphodiesterase genes are associated with susceptibility to major depression and antidepressant treatment response. Proceedings of the National Academy of Sciences of the United States of America. 2006. Wong Ma-Li, et al. [Article:17008408@PubMed]

LinkOuts

Entrez Gene:
5136
OMIM:
171890
UCSC Genome Browser:
NM_005019
RefSeq RNA:
NM_001003683
NM_005019
RefSeq Protein:
NP_001003683
NP_005010
RefSeq DNA:
AC_000045
AC_000134
NC_000002
NT_005403
NW_001838863
NW_921585
UniProtKB:
PDE1A_HUMAN (P54750)
Ensembl:
ENSG00000115252
GenAtlas:
PDE1A
GeneCard:
GC02M182971 (5136)
MutDB:
PDE1A
ALFRED:
LO001535O
HuGE:
PDE1A
Comparative Toxicogenomics Database:
5136
ModBase:
Q9C0L4
HumanCyc Gene:
HS03856
HGNC:
8774

Common Searches

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