PharmGKB contains no dosing guidelines for this gene. To report known dosing guidelines, or if you are interested in developing guidelines, click here.
PharmGKB contains no drug labels with pharmacogenomic information for this gene. To report a drug label with PGx, click here.
PharmGKB contains no clinical annotations for this gene. To report clinical variants, click here.
PharmGKB contains no genetic tests for this gene. To report genetic tests, click here.
The table below contains information about pharmacogenomic variants on PharmGKB. Please follow the link in the "Variant" column for more information about a particular variant. Each link in the "Variant" column leads to the corresponding PharmGKB Variant Page. The Variant Page contains summary data, including PharmGKB manually curated information about variant-drug pairs based on individual PubMed publications. The PMIDs for these PubMed publications can be found on the Variant Page.
The tags in the first column of the table indicate what type of information can be found on the corresponding Variant Page.
Links in the "Drugs" column lead to PharmGKB Drug Pages.
|
Variant?
(build 132) |
Alternate Names ? | Drugs ? | Alleles ? | Function ? |
Amino Acid?
Translation |
|
|---|---|---|---|---|---|---|
| rs1065776 | P2RY1:893C>T, P2RY1:C893T, c.57C>T, g.59048774C>T | C > T | Not Available | Ala19Ala | ||
| rs701265 | P2RY1:1622A>G, P2RY1:1622AG, P2RY1:A1622G, c.786A>G, g.59049503A>G | A > G | Not Available | Val262Val |
Overview
| Alternate Names: | ATP receptor; P2 purinoceptor subtype Y1; P2Y purinoceptor 1; platelet ADP receptor; purinergic receptor P2Y1 |
|---|---|
| Alternate Symbols: | P2Y1 |
| PharmGKB Accession Id: | PA32868 |
Details
| Cytogenetic Location: | chr3 : q25.2 - q25.2 |
|---|---|
| GP mRNA Boundary†: | chr3 : 152552736 - 152555845 |
| GP Gene Boundary†: | chr3 : 152542736 - 152558845 |
| Strand: | plus |
| Product Name: | ATP receptor, G-protein, P2 purinoceptor subtype Y1, P2Y purinoceptor 1, coupled, platelet ADP receptor, purinergic receptor P2Y, G-protein coupled, 1, purinergic receptor P2Y1 |
PharmGKB Curated Pathways
Pathways created internally by PharmGKB based primarily on literature evidence.
-
Platelet Aggregation Inhibitor Pathway, Pharmacodynamics
Effects of antiplatelet drugs on platelet aggregation pathway.
External Pathways
Links to non-PharmGKB pathways.
PharmGKB contains no links to external pathways for this gene. To report a pathway, click here.
LinkOuts
- Ensembl:
- ENSG00000169860
- GenAtlas:
- P2RY1
- GeneCard:
- GC03P152552 (5028)
- SOURCE:
- P2RY1
- MutDB:
- P2RY1
- PromoLign:
- ortho_1716
- ALFRED:
- LO289470E
Common Searches
Non-Curated Publications
A list of non-curated publications that mention this gene is available.