Gene:
MT-ND3
mitochondrially encoded NADH dehydrogenase 3

PharmGKB contains no dosing guidelines for this . To report known genotype-based dosing guidelines, or if you are interested in developing guidelines, click here.

PharmGKB has no annotated drug labels with pharmacogenomic information for this . If you know of a drug label with PGx, send us a message.

PharmGKB contains no Clinical Variants that meet the highest level of criteria.

Disclaimer: The PharmGKB's clinical annotations reflect expert consensus based on clinical evidence and peer-reviewed literature available at the time they are written and are intended only to assist clinicians in decision-making and to identify questions for further research. New evidence may have emerged since the time an annotation was submitted to the PharmGKB. The annotations are limited in scope and are not applicable to interventions or diseases that are not specifically identified.

The annotations do not account for individual variations among patients, and cannot be considered inclusive of all proper methods of care or exclusive of other treatments. It remains the responsibility of the health-care provider to determine the best course of treatment for a patient. Adherence to any guideline is voluntary, with the ultimate determination regarding its application to be made solely by the clinician and the patient. PharmGKB assumes no responsibility for any injury or damage to persons or property arising out of or related to any use of the PharmGKB clinical annotations, or for any errors or omissions.

? = Mouse-over for quick help

This is a non-comprehensive list of genetic tests with pharmacogenetics relevance, typically submitted by the manufacturer and manually curated by PharmGKB. The information listed is provided for educational purposes only and does not constitute an endorsement of any listed test or manufacturer.

A more complete listing of genetic tests is found at the Genetic Testing Registry (GTR).

PGx Test Variants Assayed Related Drugs?

Overview

Alternate Names:  None
Alternate Symbols:  None
PharmGKB Accession Id: PA31262

Details

Cytogenetic Location: unavailable
GP mRNA Boundary: chrM : 10061 - 10406
GP Gene Boundary: chrM : 61 - 13406
Strand: plus
The mRNA boundaries are calculated using the gene's default feature set from NCBI, mapped onto the UCSC Golden Path. PharmGKB sets gene boundaries by expanding the mRNA boundaries by no less than 10,000 bases upstream (5') and 3,000 bases downstream (3') to allow for potential regulatory regions.

PharmGKB Curated Pathways

Pathways created internally by PharmGKB based primarily on literature evidence.

PharmGKB contains no curated pathways for this gene. If you would like to volunteer to work on a pathway, please let us know.

External Pathways

Links to non-PharmGKB pathways.

  1. Electron Transport Chain - (Reactome via Pathway Interaction Database)

Publications related to MT-ND3: 1

No Dosing Guideline available No Drug Label available No Clinical Annotation available No Variant Annotation available No VIP available No VIP available
A large-scale candidate gene approach identifies SNPs in SOD2 and IL13 as predictive markers of response to preoperative chemoradiation in rectal cancer. The pharmacogenomics journal. 2010. Ho-Pun-Cheung A, et al. PubMed

LinkOuts

Entrez Gene:
4537
OMIM:
516002
UCSC Genome Browser:
NM_173710
RefSeq Protein:
810024H
AAB58950
AAK17214
AAK17227
AAK17318
AAK17344
AAK17357
AAK17370
AAK17409
AAK17448
AAK17461
AAK17539
AAK17604
AAK17708
AAK17721
AAK17747
AAK17760
AAK17773
AAK17786
AAK17838
AAL47660
AAL47662
AAL47663
AAL47664
AAL47666
AAL54404
AAL54417
AAL54443
AAL54456
AAL54495
AAL54508
AAL54547
AAL54573
AAL54599
AAL54625
AAL54664
AAL54677
AAL54690
AAL54716
AAL54742
AAL54768
AAN14554
AAN14565
AAN14631
AAN14664
AAN14675
AAN14686
AAN14697
AAN14708
AAN14719
AAN14730
AAN14741
AAN14752
AAN14763
AAN14774
AAN14796
AAN14807
AAN14818
AAN14829
AAN14873
AAN14884
AAN14917
AAN14928
AAN14950
AAN14972
AAO66625
AAO66651
AAO66664
AAO66716
AAO66729
AAO66768
AAO66833
AAO67028
AAO67054
AAO67080
AAO67105
AAO67170
AAO67196
AAO67235
AAO88287
AAO88300
AAO88313
AAO88339
AAO88352
AAO88365
AAO88378
AAO88430
AAO88443
AAO88456
AAO88482
AAO88534
AAO88573
AAO88586
AAO88612
AAO88625
AAO88651
AAO88677
AAO88729
AAO88820
AAO88833
AAO88885
AAP47887
AAP47900
AAP47913
AAP47926
AAP47939
AAP47952
AAP47978
AAP47991
AAP48004
AAP48017
AAP48030
AAP48043
AAP48069
AAP48108
AAP48121
AAP48173
AAP48212
AAP48225
AAP48264
AAP48303
AAP48316
AAP48342
AAP48355
AAP48368
AAP48407
AAP48420
AAP48432
AAP48445
AAP48458
AAP48471
AAP48510
AAP48523
AAP48536
AAP48549
AAP89043
AAP89056
AAP89069
AAP89082
AAP89095
AAP89108
AAP89121
AAP89134
AAP89147
AAP89160
AAP89173
AAP89186
AAP89199
AAP89212
AAP89225
AAP89238
AAP89251
AAP89264
AAP89277
AAP89290
AAP89303
AAP89316
AAP89329
AAP89342
AAP89355
AAP89368
AAP89381
AAP89394
AAP89407
AAP89420
AAP89433
AAP89446
AAP89459
AAP89472
AAP89485
AAP89498
AAP89511
AAP89524
AAP89537
AAP89550
AAP89563
AAP89576
AAP89589
AAP89602
AAP89615
AAP89628
AAP89641
AAP89654
AAP89667
AAP89680
AAP89693
AAP89706
AAP89719
AAP89732
AAP89745
AAP89758
AAP89771
AAP89784
AAP89797
AAP89810
AAP89823
AAP89836
AAP89849
AAP89862
AAP89992
AAP90005
AAP90018
AAP90031
AAP90044
AAP90057
AAP90070
AAP90083
AAP90096
AAP90109
AAP90122
AAP90135
AAP90148
AAP90161
AAP90174
AAP90187
AAP90200
AAP90213
AAP90226
AAP90239
AAP90252
AAP90265
AAP90447
AAP90460
AAP90473
AAP90486
AAP90616
AAP90629
AAP90642
AAP90655
AAP90668
AAP90681
AAP90694
AAP90707
AAP90720
AAP90733
AAP90746
AAP90759
AAP90772
AAP90785
AAP90798
AAP90811
AAP90824
AAP90837
AAP90850
AAP90863
AAP90876
AAP90889
AAP90902
AAP90915
AAP90954
AAP90967
AAP90980
AAP90993
AAP91006
AAP91175
AAP91188
AAP91201
AAP91214
AAP91227
AAP91240
AAP91253
AAP91266
AAP91279
AAQ19337
AAQ19350
AAQ19363
AAQ19376
AAQ19389
AAQ19402
AAQ19415
AAQ19428
AAQ19441
AAQ19454
AAQ19467
AAR91213
AAR91239
AAR91265
AAR91317
AAR91343
AAR91356
AAR92503
AAR92516
AAR92529
AAR92542
AAR92555
AAR92568
AAR92581
AAR92594
AAR92607
AAR92620
AAR92633
AAR92646
AAR92659
AAR92672
AAR92685
AAR92698
AAR92711
AAR92724
AAR92737
AAR92750
AAR92763
AAR92776
AAR92789
AAR92802
AAR92815
AAR92828
AAR92841
AAR92854
AAR92867
AAR92880
AAR92893
AAR92906
AAR92919
AAR92932
AAR92945
AAR92958
AAR92971
AAR92984
AAR92997
AAR93010
AAR93023
AAR93036
AAR93049
AAR93062
AAR93075
AAR93088
AAR93101
AAR93114
AAR93127
AAR93140
AAR93153
AAR93166
AAR93179
AAR93192
AAR93205
AAR93218
AAR93231
AAR93244
AAR93257
AAR93270
AAR93283
AAR93296
AAR93309
AAR93322
AAR93335
AAR93348
AAR93361
AAR93374
AAR93387
AAR93400
AAR93413
AAR93426
AAR93439
AAR93452
AAR93465
AAR93478
AAR93491
AAR93504
AAR93517
AAR93530
AAR93556
AAR93569
AAR93582
AAR93595
AAR93608
AAR93621
AAR93634
AAR93647
AAR93660
AAR93673
AAR93686
AAR93699
AAR93712
AAR93725
AAR93738
AAR93751
AAR93764
AAR93777
AAR93790
AAR93803
AAR93816
AAR93829
AAR93842
AAR93855
AAR94440
AAR94453
AAR94466
AAR94479
AAR94505
AAR94531
AAR94544
AAR94557
AAR94570
AAR94609
AAR94804
AAR94817
AAR94830
AAR94843
AAR94856
AAR94869
AAR94882
AAR94895
AAR94908
AAR94921
AAR94934
AAR94947
AAR94960
AAR94973
AAR94986
AAR94999
AAR95012
AAR95025
AAR95038
AAR95051
AAR95064
AAR95077
AAR95090
AAR95103
AAR95116
AAR95129
AAR95142
AAR95155
AAR95168
AAR95194
AAR95207
AAR95220
AAR95233
AAR95246
AAR95259
AAR95272
AAR95285
AAR95298
AAR95311
AAR95324
AAR95337
AAR95350
AAR95363
AAR95376
AAR95389
AAR95402
AAR95415
AAR95428
AAR95441
AAR95454
AAR95467
AAR95480
AAR95493
AAR95506
AAR95519
AAR95532
AAR95545
AAR95558
AAR95571
AAR95584
AAR95597
AAR95610
AAR95623
AAU02131
AAU02144
AAU02157
AAU02170
AAU02183
AAU02196
AAU02209
AAU02248
AAU02261
AAU02274
AAU02287
AAU02300
AAU02313
AAU02326
AAU02339
AAU02352
AAU02365
AAU02378
AAU02391
AAU02404
AAU02417
AAU02430
AAU02443
AAU02456
AAU02469
AAU02482
AAU02495
AAU02521
AAU02534
AAU02547
AAU02560
AAU02573
AAU02586
AAU02599
AAU02612
AAU02625
AAU02638
AAU02651
AAU02664
AAU02677
AAU02690
AAU02703
AAU02716
AAU02729
AAU02742
AAU02755
AAU02768
AAU02794
AAU02820
AAU02846
AAU02859
AAU02924
AAU02937
AAU02950
AAU02963
AAU02989
AAU03002
AAU03028
AAU03041
AAU03054
AAU03067
AAU03080
AAU03093
AAU12959
AAU12972
AAU12985
AAU12998
AAU13011
AAU13024
AAU13037
AAU13050
AAU13063
AAU13076
AAU13089
AAU13102
AAU13115
AAU13128
AAU13141
AAU13154
AAU13167
AAU13180
AAU13193
AAU13206
AAU13219
AAU13232
AAU13245
AAU13258
AAU13271
AAU13284
AAU13297
AAU13310
AAU13323
AAU13336
AAU13349
AAU13362
AAU13375
AAU13388
AAU13401
AAU13414
AAU13427
AAU13440
AAU13453
AAU13466
AAU13479
AAU13492
AAU13505
AAU13518
AAU13531
AAU13544
AAU13557
AAU13570
AAU13583
AAU13596
AAU13609
AAU13622
AAU13635
AAU13648
AAU13661
AAU13674
AAU13687
AAU13700
AAU13713
AAU13726
AAU13739
AAU13752
AAW58158
AAW58171
AAW58184
AAW58197
AAW58210
AAW58223
AAW58236
AAW58249
AAW58262
AAW58275
AAW58288
AAW58301
AAW58327
AAW58379
AAW58392
AAW58405
AAW58418
AAW58431
AAW58444
AAW58457
AAW58470
AAW58483
AAW58496
AAW58509
AAW58522
AAW58535
AAW58548
AAW58561
AAW58587
AAW58600
AAW58613
AAW58626
AAW58639
AAW58652
AAX47804
AAX53679
AAX53705
AAX53718
AAX53757
AAX53770
AAX53783
AAY99923
AAY99936
AAZ00612
AAZ00638
AAZ00651
AAZ00664
AAZ00781
AAZ00794
AAZ00807
AAZ00820
AAZ00833
AAZ00846
AAZ00859
AAZ00872
AAZ00885
AAZ00898
AAZ01028
AAZ01145
AAZ01158
AAZ01171
AAZ01236
AAZ01249
AAZ01262
AAZ01288
AAZ01301
AAZ01314
AAZ01327
AAZ01340
AAZ01366
AAZ01379
AAZ01431
AAZ01444
AAZ01457
AAZ01470
AAZ01483
AAZ01496
AAZ01509
AAZ01535
AAZ01548
AAZ01561
AAZ01574
AAZ01587
AAZ01600
AAZ01626
AAZ01639
AAZ01678
AAZ01691
AAZ01704
AAZ01717
AAZ01730
AAZ01743
AAZ01756
AAZ01769
AAZ01782
AAZ01795
AAZ01808
AAZ01821
AAZ02042
AAZ02068
AAZ02081
AAZ02094
AAZ02172
AAZ02185
AAZ02224
AAZ02276
AAZ02289
AAZ02315
AAZ02341
AAZ02432
AAZ02445
AAZ02458
AAZ02471
AAZ02484
AAZ02536
AAZ02952
AAZ02978
AAZ02991
AAZ03030
AAZ03043
AAZ03056
AAZ03069
AAZ03082
AAZ03095
AAZ03108
AAZ03121
AAZ03134
AAZ03147
AAZ03160
AAZ03173
AAZ03199
AAZ03238
AAZ03381
AAZ57224
AAZ57237
AAZ57250
AAZ57263
AAZ57276
AAZ57289
AAZ57302
ABA07967
ABA07980
ABA07993
ABA08019
ABB51405
ABB51418
ABB51457
ABB51470
ABB51483
ABB78098
ABB78111
ABB78124
ABB78137
ABB78150
ABB78163
ABB78176
ABB78189
ABB78202
ABB78215
ABB78228
ABB78241
ABB78254
ABB78267
ABB78280
ABB78293
ABB78306
ABB78319
ABB78332
ABB78345
ABB78358
ABB78371
ABB78384
ABB78397
ABB78410
ABB78423
ABB78436
ABB78449
ABB78462
ABB78475
ABB78488
ABB78501
ABB78514
ABB78527
ABB78540
ABB78553
ABB78566
ABB78579
ABB78592
ABB78605
ABB78618
ABB78631
ABB78644
ABB78657
ABB78670
ABB78683
ABB78696
ABB78709
ABB78722
ABB78735
ABB78748
ABB78761
ABB78774
ABB78787
ABB78800
ABB78813
ABB78826
ABB78839
ABB78852
ABB78865
ABB79476
ABB79489
ABB79502
ABB79515
ABB79528
ABB79541
ABB79554
ABB79567
ABB79580
ABB79593
ABB79606
ABB79619
ABB79671
ABB79684
ABB79697
ABB79710
ABB90912
ABB91055
ABB91081
ABB91185
ABB91276
ABB91289
ABB91328
ABC60855
ABC60868
ABC70389
ABC96417
ABC96430
ABC96443
ABC96456
ABC96469
ABC96482
ABC96508
ABC96521
ABC96560
ABC96625
ABD48569
ABD48582
ABD48647
ABD48660
ABD58964
ABD72624
ABD95693
ABD98703
ABD98716
ABD98729
ABE27867
ABE99120
ABE99133
ABE99159
ABE99172
ABE99185
ABE99211
ABE99224
ABE99237
ABE99250
ABE99263
ABE99276
ABE99289
ABE99328
ABE99341
ABE99354
ABE99367
ABE99380
ABE99393
ABE99406
ABE99419
ABE99432
ABE99445
ABF48737
ABF48750
ABF48763
ABF48776
ABF48789
ABF48802
ABF48815
ABF48828
ABF48841
ABF48854
ABF48867
ABF48893
ABF48906
ABF48919
ABF48932
ABF48945
ABF48971
ABF48984
ABF48997
ABF49023
ABF49036
ABF49049
ABF49062
ABF49075
ABF49088
ABF49101
ABF49114
ABF49127
ABF49140
ABF49153
ABF49166
ABF49192
ABF49205
ABF49218
ABF49231
ABF49244
ABF49270
ABF49283
ABF49296
ABF49309
ABF49322
ABF49335
ABF49348
ABF49361
ABF49374
ABF49387
ABF49400
ABF49426
ABF49439
ABF49452
ABF49465
ABF49478
ABF49491
ABF49504
ABF49517
ABF49530
ABF49543
ABF66155
ABF83964
ABF84050
ABG38204
ABG47405
ABG49138
ABG54136
ABG54162
ABG54201
ABG54214
ABG54240
ABG91317
ABG91330
ABG91368
ABG91380
ABI32582
ABI32608
ABI32621
ABI32634
ABI32647
ABI32660
ABI32686
ABI32725
ABI32738
ABI32923
ABI32949
ABI32962
ABI32975
ABI32988
ABI33001
ABI33014
ABI33027
ABI33040
ABI51801
ABI51814
ABI51827
ABI51840
ABI51853
ABI51866
ABI51879
ABI51892
ABI51905
ABI51918
ABI51931
ABJ89623
ABJ89636
ABJ90968
ABJ90981
ABJ90994
ABJ99105
ABJ99118
ABJ99131
ABJ99144
ABJ99157
ABJ99170
ABJ99183
ABJ99196
ABJ99209
ABJ99222
ABJ99235
ABJ99248
ABJ99274
ABJ99287
ABJ99313
ABJ99326
ABJ99339
ABJ99352
ABJ99365
ABJ99378
ABJ99391
ABJ99404
ABJ99417
ABJ99430
ABJ99443
ABJ99456
ABK28798
ABK28811
ABL60015
ABL60028
ABL60054
ABL60067
ABL60080
ABL60132
ABL60171
ABL60184
ABL60223
ABL60275
ABL60288
ABL60301
ABL60314
ABL60327
ABL60353
ABL60379
ABL60405
ABL60431
ABL60470
ABL60483
ABL60496
ABL60509
ABL60535
ABL60574
ABL60600
ABL60639
ABL60704
ABL60743
ABL60808
ABL60821
ABL73225
ABL73238
ABL73264
ABL73277
ABL73290
ABL73303
ABL73329
ABL73394
ABL73407
ABL73433
ABL73459
ABL73472
ABL73485
ABL73498
ABL73511
ABL73524
ABL73537
ABL73550
ABL73576
ABL73589
ABL73602
ABL73615
ABL73628
ABL73654
ABL73667
ABL73680
ABL73693
ABL73706
ABL73732
ABL73745
ABL73758
ABL73771
ABM68656
ABM68669
ABM68682
ABM68695
ABM68708
ABM68721
ABM68734
ABM68747
ABM68760
ABM68773
ABM68786
ABM68799
ABM68812
ABM68825
ABM68838
ABM68851
ABM68864
ABM68877
ABM68890
ABM68903
ABM68916
ABM68929
ABM79843
ABM79856
ABM92871
ABN10373
ABN10386
ABN13440
ABN13453
ABN13466
ABN13479
ABN13492
ABN13505
ABN13518
ABN13531
ABN42442
ABN42455
ABN42468
ABN42481
ABN45810
ABN45823
ABN58526
ABN72612
ABN72625
ABN72638
ABN72690
ABN72703
ABN72716
ABN88616
ABO09905
ABO09944
ABO13984
ABO14153
ABO31021
ABO31034
ABO34036
ABO36803
ABO36816
ABO36829
ABO36842
ABO36855
ABO36868
ABO36920
ABO36933
ABO36946
ABO36959
ABO36972
ABO36985
ABO37037
ABO37050
ABO40027
ABO40040
ABO40053
ABO69260
ABO70874
ABO70887
ABO70900
ABO86148
ABO86161
ABO86186
ABP57116
ABP99069
ABP99095
ABP99147
ABP99173
ABP99186
ABP99199
ABP99212
ABP99225
ABP99238
ABP99251
ABP99264
ABP99277
ABP99290
ABP99316
ABP99329
ABP99355
ABP99381
ABP99420
ABP99433
ABP99446
ABP99459
ABP99472
ABP99498
ABP99511
ABP99524
ABP99537
ABP99550
ABP99563
ABP99576
ABP99589
ABP99602
ABP99615
ABP99628
ABP99641
ABP99667
ABQ09381
ABQ45182
ABQ45195
ABQ45208
ABQ45221
ABR10778
ABR10791
ABR10817
ABR57517
ABR57543
ABR57556
ABR57608
ABR57621
ABR57634
ABR57647
ABR57660
ABR57673
ABR57686
ABR57699
ABR57738
ABR57776
ABR57802
ABR57815
ABR57828
ABR57841
ABR57854
ABR57867
ABR57880
ABR57893
ABR57906
ABR57919
ABR57932
ABR57958
ABR57971
ABR57984
ABR57997
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BAE15406
BAE15419
BAE15458
BAE15471
BAE15549
BAE15588
BAE15601
BAE15627
BAE15666
BAE15679
BAE15692
BAE15705
BAE15744
BAE15770
BAE15848
BAE15874
BAE15913
BAE15939
BAE15952
BAG14439
BAG14517
BAG14530
BAG14569
BAG14582
BAG14634
BAG14686
BAG14855
BAG14894
BAG14920
BAG14959
BAG14972
BAG14985
BAG15024
BAG15141
BAG15193
BAG15219
BAG15232
BAG15271
BAG15310
BAG15336
BAG15349
BAG15362
BAG15375
BAG15401
BAG15427
BAG15479
BAG15492
BAG15505
BAG15609
BAG15648
BAG15804
BAG38805
BAG38844
BAG38909
BAG38961
BAG38987
BAG39039
BAG39117
BAG39143
BAG39182
BAG39195
BAG39208
BAG39221
BAG39286
BAG39351
BAG39377
BAG39390
BAG39416
BAG39429
BAG39442
BAH11009
BAH11022
BAH11035
BAH11048
BAH11061
BAH11074
CAA24033
CAH59700
CAJ97459
CAJ97472
CAJ97485
CAJ97498
CAJ97511
CAJ97524
CAJ97537
CAJ97550
CAJ97563
CAJ97576
CAJ97589
CAJ97602
CAJ97641
CAJ97654
CAJ97667
CAJ97680
CAJ97693
CAJ97706
CAJ97719
CAJ97732
CAJ97745
CAJ97758
CAJ97771
CAJ97784
CAJ97797
CAJ97810
CAJ97823
CAJ97836
CAJ97862
CAJ97875
CAJ97888
CAJ97901
CAJ97914
CAJ97927
CAJ97940
CAJ97953
CAJ97966
CAJ97979
CAJ97992
CAJ98005
CAJ98018
CAJ98031
CAJ98044
CAJ98057
CAJ98070
CAJ98083
CAJ98096
CAJ98109
CAJ98122
CAJ98135
CAJ98148
CAJ98161
CAJ98187
CAJ98200
CAJ98213
CAJ98226
CAJ98239
CAJ98252
CAJ98265
CAJ98278
CAJ98291
CAJ98304
CAJ98317
CAJ98330
CAJ98343
CAJ98356
CAJ98369
CAJ98382
CAJ98395
CAJ98408
CAJ98421
CAJ98434
CAJ98447
CAK19123
CAK19136
CAK19149
CAK19162
CAK19175
CAK19188
CAK19214
CAK19227
CAK19240
CAK19253
CAK19266
CAK19279
CAK19292
CAK19305
DNHUN3
NP_536850
P03897
YP_003024033
RefSeq DNA:
NC_001807
Ensembl:
ENSG00000198840
GenAtlas:
MT-ND3
GeneCard:
MT-ND3
MutDB:
MT-ND3
HuGE:
MT-ND3

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