Gene:
KRT86
keratin 86

PharmGKB contains no dosing guidelines for this . To report known genotype-based dosing guidelines, or if you are interested in developing guidelines, click here.

PharmGKB has no annotated drug labels with pharmacogenomic information for this . If you know of a drug label with PGx, send us a message.

PharmGKB contains no Clinical Variants that meet the highest level of criteria.

Disclaimer: The PharmGKB's clinical annotations reflect expert consensus based on clinical evidence and peer-reviewed literature available at the time they are written and are intended only to assist clinicians in decision-making and to identify questions for further research. New evidence may have emerged since the time an annotation was submitted to the PharmGKB. The annotations are limited in scope and are not applicable to interventions or diseases that are not specifically identified.

The annotations do not account for individual variations among patients, and cannot be considered inclusive of all proper methods of care or exclusive of other treatments. It remains the responsibility of the health-care provider to determine the best course of treatment for a patient. Adherence to any guideline is voluntary, with the ultimate determination regarding its application to be made solely by the clinician and the patient. PharmGKB assumes no responsibility for any injury or damage to persons or property arising out of or related to any use of the PharmGKB clinical annotations, or for any errors or omissions.

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This is a non-comprehensive list of genetic tests with pharmacogenetics relevance, typically submitted by the manufacturer and manually curated by PharmGKB. The information listed is provided for educational purposes only and does not constitute an endorsement of any listed test or manufacturer.

A more complete listing of genetic tests is found at the Genetic Testing Registry (GTR).

PGx Test Variants Assayed Related Drugs?

Overview

Alternate Names:  hard keratin type II 6
Alternate Symbols:  Hb6; MNX
PharmGKB Accession Id: PA30252

Details

Cytogenetic Location: chr12 : q13.13 - q13.13
GP mRNA Boundary: chr12 : 52695649 - 52702947
GP Gene Boundary: chr12 : 52685649 - 52705947
Strand: plus
The mRNA boundaries are calculated using the gene's default feature set from NCBI, mapped onto the UCSC Golden Path. PharmGKB sets gene boundaries by expanding the mRNA boundaries by no less than 10,000 bases upstream (5') and 3,000 bases downstream (3') to allow for potential regulatory regions.

LinkOuts

Entrez Gene:
3892
OMIM:
158000
601928
UCSC Genome Browser:
NM_002284
RefSeq RNA:
NM_002284
RefSeq Protein:
NP_002275
RefSeq DNA:
AC_000055
AC_000144
NC_000012
NG_008086
NT_029419
NW_001838057
NW_001838058
NW_925351
NW_925352
UniProtKB:
KRT86_HUMAN (O43790)
Ensembl:
ENSG00000170442
ENSG00000258832
GenAtlas:
KRT86
GeneCard:
KRT86
MutDB:
KRT86
ALFRED:
LO058402T
HuGE:
KRT86
Comparative Toxicogenomics Database:
3892
ModBase:
O43790
HumanCyc Gene:
HS10129
HGNC:
6463

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