inositol 1,4,5-trisphosphate receptor, type 1
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PharmGKB contains no Clinical Variants that meet the highest level of criteria.
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This is a non-comprehensive list of genetic tests with pharmacogenetics relevance, typically submitted by the manufacturer and manually curated by PharmGKB. The information listed is provided for educational purposes only and does not constitute an endorsement of any listed test or manufacturer.
A more complete listing of genetic tests is found at the Genetic Testing Registry (GTR).
|PGx Test||Variants Assayed||Related Drugs?|
|Alternate Symbols: ||IP3R1; Insp3r1|
|PharmGKB Accession Id:||PA29978|
|Cytogenetic Location:||chr3 : p26.1 - p26.1|
|GP mRNA Boundary†:||chr3 : 4535032 - 4889524|
|GP Gene Boundary†:||chr3 : 4525032 - 4892524|
PharmGKB Curated Pathways
Pathways created internally by PharmGKB based primarily on literature evidence.
Beta-agonist/Beta-blocker Pathway, Pharmacodynamics
Simplified pharmacodynamic pathway of drug action on beta 2 adrenergic receptor in a stylized airway cell.
Links to non-PharmGKB pathways.
Publications related to ITPR1: 3
The following icons indicate that data of a certain type is available:
- DG Dosing Guideline information is available
- DL Drug Label information is available
- CA High-level Clinical Annotation is available
- VA Variant Annotation is available
- VIP VIP information is available
- PW Pathway is available
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||Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling. Cancer cell. 2002. Yeoh Eng-Juh, et al.|
||Airway wall remodelling and hyperresponsiveness: modelling remodelling in vitro and in vivo. Pulmonary pharmacology & therapeutics. 2001. Stewart A G.|
||Regulation of nerve growth mediated by inositol 1,4,5-trisphosphate receptors in growth cones. Science (New York, N.Y.). 1998. Takei K, et al.|