Gene:
HSPB1
heat shock 27kDa protein 1

PharmGKB contains no dosing guidelines for this . To report known genotype-based dosing guidelines, or if you are interested in developing guidelines, click here.

PharmGKB has no annotated drug labels with pharmacogenomic information for this . If you know of a drug label with PGx, send us a message.

PharmGKB contains no Clinical Variants that meet the highest level of criteria.

Disclaimer: The PharmGKB's clinical annotations reflect expert consensus based on clinical evidence and peer-reviewed literature available at the time they are written and are intended only to assist clinicians in decision-making and to identify questions for further research. New evidence may have emerged since the time an annotation was submitted to the PharmGKB. The annotations are limited in scope and are not applicable to interventions or diseases that are not specifically identified.

The annotations do not account for individual variations among patients, and cannot be considered inclusive of all proper methods of care or exclusive of other treatments. It remains the responsibility of the health-care provider to determine the best course of treatment for a patient. Adherence to any guideline is voluntary, with the ultimate determination regarding its application to be made solely by the clinician and the patient. PharmGKB assumes no responsibility for any injury or damage to persons or property arising out of or related to any use of the PharmGKB clinical annotations, or for any errors or omissions.

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This is a non-comprehensive list of genetic tests with pharmacogenetics relevance, typically submitted by the manufacturer and manually curated by PharmGKB. The information listed is provided for educational purposes only and does not constitute an endorsement of any listed test or manufacturer.

A more complete listing of genetic tests is found at the Genetic Testing Registry (GTR).

PGx Test Variants Assayed Related Drugs?

Overview

Alternate Names:  None
Alternate Symbols:  HSP27; HSP28; Hs.76067; Hsp25
PharmGKB Accession Id: PA29511

Details

Cytogenetic Location: chr7 : q11.23 - q11.23
GP mRNA Boundary: chr7 : 75931875 - 75933614
GP Gene Boundary: chr7 : 75921875 - 75936614
Strand: plus
The mRNA boundaries are calculated using the gene's default feature set from NCBI, mapped onto the UCSC Golden Path. PharmGKB sets gene boundaries by expanding the mRNA boundaries by no less than 10,000 bases upstream (5') and 3,000 bases downstream (3') to allow for potential regulatory regions.

LinkOuts

Entrez Gene:
3315
OMIM:
602195
606595
608634
UCSC Genome Browser:
NM_001540
RefSeq RNA:
NM_001540
RefSeq Protein:
NP_001531
RefSeq DNA:
AC_000050
AC_000068
AC_000139
NC_000007
NG_008995
NT_007933
NT_079595
NW_001839047
NW_923484
UniProtKB:
HSPB1_HUMAN (P04792)
Ensembl:
ENSG00000106211
GenAtlas:
HSPB1
GeneCard:
HSPB1
MutDB:
HSPB1
ALFRED:
LO209082V
HuGE:
HSPB1
Comparative Toxicogenomics Database:
3315
ModBase:
P04792
HumanCyc Gene:
HS02871
HGNC:
5246

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