Gene:
GPR18
G protein-coupled receptor 18

PharmGKB contains no dosing guidelines for this . To report known genotype-based dosing guidelines, or if you are interested in developing guidelines, click here.

PharmGKB contains no drug labels with pharmacogenomic information for this . To report a drug label with PGx, click here.

Disclaimer: The PharmGKB's clinical annotations reflect expert consensus based on clinical evidence and peer-reviewed literature available at the time they are written and are intended only to assist clinicians in decision-making and to identify questions for further research. New evidence may have emerged since the time an annotation was submitted to the PharmGKB. The annotations are limited in scope and are not applicable to interventions or diseases that are not specifically identified.

The annotations do not account for individual variations among patients, and cannot be considered inclusive of all proper methods of care or exclusive of other treatments. It remains the responsibility of the health-care provider to determine the best course of treatment for a patient. Adherence to any guideline is voluntary, with the ultimate determination regarding its application to be made solely by the clinician and the patient. PharmGKB assumes no responsibility for any injury or damage to persons or property arising out of or related to any use of the PharmGKB clinical annotations, or for any errors or omissions.

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This is a non-comprehensive list of genetic tests with pharmacogenetics relevance, typically submitted by the manufacturer and manually curated by PharmGKB. The information listed is provided for educational purposes only and does not constitute an endorsement of any listed test or manufacturer.

A more complete listing of genetic tests is found at the Genetic Testing Registry (GTR).

PGx Test Variants Assayed Related Drugs?

Overview

Alternate Names:  None
Alternate Symbols:  None
PharmGKB Accession Id: PA28860

Details

Cytogenetic Location: chr13 : q32.3 - q32.3
GP mRNA Boundary: chr13 : 99906967 - 99910682
GP Gene Boundary: chr13 : 99903967 - 99920682
Strand: minus
The mRNA boundaries are calculated using the gene's default feature set from NCBI, mapped onto the UCSC Golden Path. PharmGKB sets gene boundaries by expanding the mRNA boundaries by no less than 10,000 bases upstream (5') and 3,000 bases downstream (3') to allow for potential regulatory regions.

LinkOuts

Entrez Gene:
2841
OMIM:
602042
UCSC Genome Browser:
NM_005292
RefSeq RNA:
NM_001098200
NM_005292
RefSeq Protein:
NP_001091670
NP_005283
RefSeq DNA:
AC_000056
AC_000145
NC_000013
NT_009952
NW_001838084
NW_925517
UniProtKB:
GPR18_HUMAN (Q14330)
Ensembl:
ENSG00000125245
GenAtlas:
GPR18
GeneCard:
GPR18
MutDB:
GPR18
ALFRED:
LO102273P
HuGE:
GPR18
ModBase:
Q14330
HumanCyc Gene:
HS04861
IUPHAR Receptor:
GPR18 (89)
HGNC:
4472

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