PharmGKB contains no dosing guidelines for this gene. To report known dosing guidelines, or if you are interested in developing guidelines, click here.
PharmGKB contains no drug labels with pharmacogenomic information for this gene. To report a drug label with PGx, click here.
PharmGKB contains no clinical annotations for this gene. To report clinical variants, click here.
PharmGKB contains no genetic tests for this gene. To report genetic tests, click here.
Overview
| Alternate Names: | CH24H; cholesterol 24-hydroxylase; cytochrome P450 46A1; cytochrome P450, family 46; cytochrome P450, subfamily 46 (cholesterol 24-hydroxylase) |
|---|---|
| Alternate Symbols: | CP46; CYP46 |
| PharmGKB Accession Id: | PA27117 |
Details
| Cytogenetic Location: | chr14 : q32.2 - q32.2 |
|---|---|
| GP mRNA Boundary†: | chr14 : 100150755 - 100193638 |
| GP Gene Boundary†: | chr14 : 100140755 - 100196638 |
| Strand: | plus |
| Product Name: | No data available |
PharmGKB Curated Pathways
Pathways created internally by PharmGKB based primarily on literature evidence.
PharmGKB contains no curated pathways for this gene. If you would like to volunteer to work on a pathway, please let us know.
External Pathways
Links to non-PharmGKB pathways.
Publications related to CYP46A1: 1
|
Cytochrome P450 and gene activation--from pharmacology to cholesterol elimination and regression of atherosclerosis. European journal of clinical pharmacology. 2008. Luoma Pauli V. [Article:18633604@PubMed] |
LinkOuts
- RefSeq DNA:
- AC_000057
- AC_000146
- NC_000014
- NG_007963
- NT_026437
- NW_001838115
- NW_925561
- UniProtKB:
- CP46A_HUMAN (Q9Y6A2)
- Ensembl:
- ENSG00000036530
- GeneCard:
- GC14P100150 (10858)
- MutDB:
- CYP46A1