Gene:
CNOT6
CCR4-NOT transcription complex, subunit 6

PharmGKB contains no dosing guidelines for this . To report known genotype-based dosing guidelines, or if you are interested in developing guidelines, click here.

PharmGKB contains no drug labels with pharmacogenomic information for this . To report a drug label with PGx, click here.

Disclaimer: The PharmGKB's clinical annotations reflect expert consensus based on clinical evidence and peer-reviewed literature available at the time they are written and are intended only to assist clinicians in decision-making and to identify questions for further research. New evidence may have emerged since the time an annotation was submitted to the PharmGKB. The annotations are limited in scope and are not applicable to interventions or diseases that are not specifically identified.

The annotations do not account for individual variations among patients, and cannot be considered inclusive of all proper methods of care or exclusive of other treatments. It remains the responsibility of the health-care provider to determine the best course of treatment for a patient. Adherence to any guideline is voluntary, with the ultimate determination regarding its application to be made solely by the clinician and the patient. PharmGKB assumes no responsibility for any injury or damage to persons or property arising out of or related to any use of the PharmGKB clinical annotations, or for any errors or omissions.

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This is a non-comprehensive list of genetic tests with pharmacogenetics relevance, typically submitted by the manufacturer and manually curated by PharmGKB. The information listed is provided for educational purposes only and does not constitute an endorsement of any listed test or manufacturer.

A more complete listing of genetic tests is found at the Genetic Testing Registry (GTR).

PGx Test Variants Assayed Related Drugs?

Overview

Alternate Names:  None
Alternate Symbols:  CCR4; KIAA1194
PharmGKB Accession Id: PA26677

Details

Cytogenetic Location: chr5 : q35.3 - q35.3
GP mRNA Boundary: chr5 : 179921417 - 180005353
GP Gene Boundary: chr5 : 179911417 - 180008353
Strand: plus
The mRNA boundaries are calculated using the gene's default feature set from NCBI, mapped onto the UCSC Golden Path. PharmGKB sets gene boundaries by expanding the mRNA boundaries by no less than 10,000 bases upstream (5') and 3,000 bases downstream (3') to allow for potential regulatory regions.

LinkOuts

Entrez Gene:
57472
OMIM:
608951
RefSeq RNA:
NM_015455
RefSeq Protein:
NP_056270
RefSeq DNA:
AC_000048
AC_000137
NC_000005
NT_023133
NW_001838967
NW_922818
UniProtKB:
CNOT6_HUMAN (Q9ULM6)
Ensembl:
ENSG00000113300
GenAtlas:
CNOT6
GeneCard:
CNOT6
MutDB:
CNOT6
ALFRED:
LO015778C
HuGE:
CNOT6
ModBase:
Q9ULM6
HGNC:
14099

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