Gene:
CAMK1
calcium/calmodulin-dependent protein kinase I

PharmGKB contains no dosing guidelines for this . To report known genotype-based dosing guidelines, or if you are interested in developing guidelines, click here.

PharmGKB contains no drug labels with pharmacogenomic information for this . To report a drug label with PGx, click here.

Disclaimer: The PharmGKB's clinical annotations reflect expert consensus based on clinical evidence and peer-reviewed literature available at the time they are written and are intended only to assist clinicians in decision-making and to identify questions for further research. New evidence may have emerged since the time an annotation was submitted to the PharmGKB. The annotations are limited in scope and are not applicable to interventions or diseases that are not specifically identified.

The annotations do not account for individual variations among patients, and cannot be considered inclusive of all proper methods of care or exclusive of other treatments. It remains the responsibility of the health-care provider to determine the best course of treatment for a patient. Adherence to any guideline is voluntary, with the ultimate determination regarding its application to be made solely by the clinician and the patient. PharmGKB assumes no responsibility for any injury or damage to persons or property arising out of or related to any use of the PharmGKB clinical annotations, or for any errors or omissions.

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This is a non-comprehensive list of genetic tests with pharmacogenetics relevance, typically submitted by the manufacturer and manually curated by PharmGKB. The information listed is provided for educational purposes only and does not constitute an endorsement of any listed test or manufacturer.

A more complete listing of genetic tests is found at the Genetic Testing Registry (GTR).

PGx Test Variants Assayed Related Drugs?

Overview

Alternate Names:  None
Alternate Symbols:  CaMKI
PharmGKB Accession Id: PA26048

Details

Cytogenetic Location: chr3 : p25.3 - p25.3
GP mRNA Boundary: chr3 : 9799029 - 9811668
GP Gene Boundary: chr3 : 9796029 - 9821668
Strand: minus
The mRNA boundaries are calculated using the gene's default feature set from NCBI, mapped onto the UCSC Golden Path. PharmGKB sets gene boundaries by expanding the mRNA boundaries by no less than 10,000 bases upstream (5') and 3,000 bases downstream (3') to allow for potential regulatory regions.

PharmGKB Curated Pathways

Pathways created internally by PharmGKB based primarily on literature evidence.

  1. EGFR Inhibitor Pathway, Pharmacodynamics
    Model non-tissue specific cancer cell displaying genes that may be involved in the treatment using epidermal growth factor receptor specific tyrosine kinase inhibitors or monoclonal antibodies.

External Pathways

Links to non-PharmGKB pathways.

PharmGKB contains no links to external pathways for this gene. To report a pathway, click here.

Publications related to CAMK1: 1

No Dosing Guideline available No Drug Label available No Clinical Annotation available No Variant Annotation available No VIP available No VIP available
The regulation of aldosterone synthase expression. Molecular and cellular endocrinology. 2004. Bassett Mary H, et al. PubMed

LinkOuts

Entrez Gene:
8536
OMIM:
604998
UCSC Genome Browser:
NM_003656
RefSeq RNA:
NM_003656
RefSeq Protein:
NP_003647
RefSeq DNA:
AC_000046
AC_000135
NC_000003
NT_022517
NW_001838876
NW_921651
UniProtKB:
B0YIY3_HUMAN (B0YIY3)
KCC1A_HUMAN (Q14012)
Ensembl:
ENSG00000134072
GenAtlas:
CAMK1
GeneCard:
CAMK1
MutDB:
CAMK1
ALFRED:
LO012766W
HuGE:
CAMK1
Comparative Toxicogenomics Database:
8536
ModBase:
Q14012
HumanCyc Gene:
HS05815
HGNC:
1459

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