PharmGKB contains no dosing guidelines for this gene. To report known dosing guidelines, or if you are interested in developing guidelines, click here.
PharmGKB contains no drug labels with pharmacogenomic information for this gene. To report a drug label with PGx, click here.
PharmGKB contains no clinical annotations for this gene. To report clinical variants, click here.
PharmGKB contains no genetic tests for this gene. To report genetic tests, click here.
Overview
| Alternate Names: | Alcohol dehydrogenase (class III), chi polypeptide; FALDH; GSH-FDH; S-(hydroxymethyl)glutathione dehydrogenase; alcohol dehydrogenase (class III), chi polypeptide; alcohol dehydrogenase 5, chi polypeptide; alcohol dehydrogenase class chi chain; alcohol dehydrogenase class-3; alcohol dehydrogenase class-III; clutathione-dependent formaldehyde dehydrogenase; formaldehyde dehydrogenase; glutathione-dependent formaldehyde dehydrogenase |
|---|---|
| Alternate Symbols: | ADH-3; ADHX; FDH; GSNOR |
| PharmGKB Accession Id: | PA24574 |
Details
| Cytogenetic Location: | chr4 : q23 - q23 |
|---|---|
| GP mRNA Boundary†: | chr4 : 99992129 - 100009931 |
| GP Gene Boundary†: | chr4 : 99989129 - 100019931 |
| Strand: | minus |
| Product Name: | No data available |
PharmGKB Curated Pathways
Pathways created internally by PharmGKB based primarily on literature evidence.
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Cyclophosphamide Pathway, Pharmacodynamics
Model non-tissue-specific cancer cell displaying genes which may be involved in the cyclophosphamide pathway.
External Pathways
Links to non-PharmGKB pathways.
PharmGKB contains no links to external pathways for this gene. To report a pathway, click here.
Publications related to ADH5: 5
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Influence of gene-gene interactions on response to albuterol therapy. Pharmacogenomics. 2011. Moore Paul E. [Article:21174616@PubMed] |
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The pharmacogenetics and pharmacogenomics of asthma therapy. The pharmacogenomics journal. 2011. Tse S M, et al. [Article:21987090@PubMed] |
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GSNO reductase and beta2-adrenergic receptor gene-gene interaction: bronchodilator responsiveness to albuterol. Pharmacogenetics and genomics. 2010. Choudhry Shweta, et al. [Article:20335826@PubMed] |
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Multiple ADH genes modulate risk for drug dependence in both African- and European-Americans. Human molecular genetics. 2007. Luo Xingguang, et al. [Article:17185388@PubMed] |
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Diplotype trend regression analysis of the ADH gene cluster and the ALDH2 gene: multiple significant associations with alcohol dependence. American journal of human genetics. 2006. Luo Xingguang, et al. [Article:16685648@PubMed] |
LinkOuts
- UniProtKB:
- ADHX_HUMAN (P11766)
- Q6IRT1_HUMAN (Q6IRT1)
- Ensembl:
- ENSG00000197894
- GenAtlas:
- ADH5
- GeneCard:
- GC04M099992 (128)
- MutDB:
- ADH5
- ALFRED:
- LO000424K