PharmGKB contains no dosing guidelines for this gene. To report known dosing guidelines, or if you are interested in developing guidelines, click here.
PharmGKB contains no drug labels with pharmacogenomic information for this gene. To report a drug label with PGx, click here.
PharmGKB contains no clinical annotations for this gene. To report clinical variants, click here.
PharmGKB contains no genetic tests for this gene. To report genetic tests, click here.
The table below contains information about pharmacogenomic variants on PharmGKB. Please follow the link in the "Variant" column for more information about a particular variant. Each link in the "Variant" column leads to the corresponding PharmGKB Variant Page. The Variant Page contains summary data, including PharmGKB manually curated information about variant-drug pairs based on individual PubMed publications. The PMIDs for these PubMed publications can be found on the Variant Page.
The tags in the first column of the table indicate what type of information can be found on the corresponding Variant Page.
Links in the "Drugs" column lead to PharmGKB Drug Pages.
|
Variant?
(build 132) |
Alternate Names ? | Drugs ? | Alleles ? | Function ? |
Amino Acid?
Translation |
|
|---|---|---|---|---|---|---|
| rs1662060 | T/C | Not Available | ||||
| rs283411 | C/A | Not Available | ||||
| rs283416 | G/A | Not Available | ||||
| rs698 | ADH1C*2, c.1048A>G, g.18129A>G, g.24808510T>A, g.24808510T>C, p.Ile350Val | T > C | Missense | Ile350Val |
Overview
| Alternate Names: | ADH, gamma subunit; OTTHUMP00000220209; alcohol dehydrogenase 1C; alcohol dehydrogenase 1C, gamma polypeptide; alcohol dehydrogenase 3; alcohol dehydrogenase 3 (class I), gamma polypeptide; alcohol dehydrogenase subunit gamma; aldehyde reductase |
|---|---|
| Alternate Symbols: | ADH3 |
| PharmGKB Accession Id: | PA24572 |
Details
| Cytogenetic Location: | chr4 : q23 - q23 |
|---|---|
| GP mRNA Boundary†: | chr4 : 100257649 - 100273917 |
| GP Gene Boundary†: | chr4 : 100254649 - 100283917 |
| Strand: | minus |
| Product Name: | ADH, gamma subunit, alcohol dehydrogenase 3, alcohol dehydrogenase 3 (class I), gamma polypeptide, aldehyde reductase, class I alcohol dehydrogenase, gamma subunit |
PharmGKB Curated Pathways
Pathways created internally by PharmGKB based primarily on literature evidence.
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Cyclophosphamide Pathway, Pharmacodynamics
Model non-tissue-specific cancer cell displaying genes which may be involved in the cyclophosphamide pathway.
External Pathways
Links to non-PharmGKB pathways.
Downloads
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LinkOuts
- RefSeq DNA:
- AC_000047
- AC_000136
- NC_000004
- NG_011718
- NT_016354
- NW_001838915
- NW_922162
- UniProtKB:
- ADH1G_HUMAN (P00326)
- GenAtlas:
- ADH1C
- GeneCard:
- GC04M100257 (126)
- SOURCE:
- ADH1C
Common Searches
Non-Curated Publications
A list of non-curated publications that mention this gene is available.