Gene:
RDH11
retinol dehydrogenase 11 (all-trans/9-cis/11-cis)

PharmGKB contains no dosing guidelines for this . To report known genotype-based dosing guidelines, or if you are interested in developing guidelines, click here.

PharmGKB contains no drug labels with pharmacogenomic information for this . To report a drug label with PGx, click here.

Disclaimer: The PharmGKB's clinical annotations reflect expert consensus based on clinical evidence and peer-reviewed literature available at the time they are written and are intended only to assist clinicians in decision-making and to identify questions for further research. New evidence may have emerged since the time an annotation was submitted to the PharmGKB. The annotations are limited in scope and are not applicable to interventions or diseases that are not specifically identified.

The annotations do not account for individual variations among patients, and cannot be considered inclusive of all proper methods of care or exclusive of other treatments. It remains the responsibility of the health-care provider to determine the best course of treatment for a patient. Adherence to any guideline is voluntary, with the ultimate determination regarding its application to be made solely by the clinician and the patient. PharmGKB assumes no responsibility for any injury or damage to persons or property arising out of or related to any use of the PharmGKB clinical annotations, or for any errors or omissions.

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This is a non-comprehensive list of genetic tests with pharmacogenetics relevance, typically submitted by the manufacturer and manually curated by PharmGKB. The information listed is provided for educational purposes only and does not constitute an endorsement of any listed test or manufacturer.

A more complete listing of genetic tests is found at the Genetic Testing Registry (GTR).

PGx Test Variants Assayed Related Drugs?

Overview

Alternate Names:  androgen-regulated short-chain dehydrogenase/reductase 1; short chain dehydrogenase/reductase family 7C, member 1
Alternate Symbols:  ARSDR1; MDT1; SDR7C1
PharmGKB Accession Id: PA134981588

Details

Cytogenetic Location: chr14 : q24.1 - q24.1
GP mRNA Boundary: chr14 : 68143517 - 68162510
GP Gene Boundary: chr14 : 68140517 - 68172510
Strand: minus
The mRNA boundaries are calculated using the gene's default feature set from NCBI, mapped onto the UCSC Golden Path. PharmGKB sets gene boundaries by expanding the mRNA boundaries by no less than 10,000 bases upstream (5') and 3,000 bases downstream (3') to allow for potential regulatory regions.

LinkOuts

Entrez Gene:
51109
OMIM:
607849
RefSeq RNA:
NM_016026
RefSeq Protein:
NP_057110
RefSeq DNA:
AC_000057
AC_000146
NC_000014
NT_026437
NW_001838112
NW_925561
UniProtKB:
RDH11_HUMAN (Q8TC12)
Ensembl:
ENSG00000072042
GeneCard:
RDH11
ALFRED:
LO218138X
HuGE:
RDH11
Comparative Toxicogenomics Database:
51109
ModBase:
Q8TC12
HumanCyc Gene:
HS01050
HGNC:
17964

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