Gene:
CARD10
caspase recruitment domain family, member 10

PharmGKB contains no dosing guidelines for this . To report known genotype-based dosing guidelines, or if you are interested in developing guidelines, click here.

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Disclaimer: The PharmGKB's clinical annotations reflect expert consensus based on clinical evidence and peer-reviewed literature available at the time they are written and are intended only to assist clinicians in decision-making and to identify questions for further research. New evidence may have emerged since the time an annotation was submitted to the PharmGKB. The annotations are limited in scope and are not applicable to interventions or diseases that are not specifically identified.

The annotations do not account for individual variations among patients, and cannot be considered inclusive of all proper methods of care or exclusive of other treatments. It remains the responsibility of the health-care provider to determine the best course of treatment for a patient. Adherence to any guideline is voluntary, with the ultimate determination regarding its application to be made solely by the clinician and the patient. PharmGKB assumes no responsibility for any injury or damage to persons or property arising out of or related to any use of the PharmGKB clinical annotations, or for any errors or omissions.

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This is a non-comprehensive list of genetic tests with pharmacogenetics relevance, typically submitted by the manufacturer and manually curated by PharmGKB. The information listed is provided for educational purposes only and does not constitute an endorsement of any listed test or manufacturer.

A more complete listing of genetic tests is found at the Genetic Testing Registry (GTR).

PGx Test Variants Assayed Related Drugs?

Overview

Alternate Names:  None
Alternate Symbols:  BIMP1; CARMA3
PharmGKB Accession Id: PA134927444

Details

Cytogenetic Location: chr22 : q13.1 - q13.1
GP mRNA Boundary: chr22 : 37886400 - 37915210
GP Gene Boundary: chr22 : 37883400 - 37925210
Strand: minus
The mRNA boundaries are calculated using the gene's default feature set from NCBI, mapped onto the UCSC Golden Path. PharmGKB sets gene boundaries by expanding the mRNA boundaries by no less than 10,000 bases upstream (5') and 3,000 bases downstream (3') to allow for potential regulatory regions.

LinkOuts

Entrez Gene:
29775
OMIM:
607209
RefSeq RNA:
NM_014550
RefSeq Protein:
NP_055365
RefSeq DNA:
AC_000065
AC_000154
NC_000022
NT_011520
NW_001838745
NW_927628
UniProtKB:
CAR10_HUMAN (Q9BWT7)
Ensembl:
ENSG00000100065
GeneCard:
CARD10
ALFRED:
LO144843Y
HuGE:
CARD10
Comparative Toxicogenomics Database:
29775
ModBase:
Q9BWT7
HumanCyc Gene:
HS01966
HGNC:
16422

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