Overview
| Alternate Names: | ATPase, Ca++ dependent, slow-twitch, cardiac muscle-2; ATPase, Ca++ transporting, slow twitch 2; SR Ca(2+)-ATPase 2; calcium pump 2; calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform; cardiac Ca2+ ATPase; endoplasmic reticulum class 1/2 Ca(2+) ATPase; keratosis follicularis; sarcoplasmic/endoplasmic reticulum calcium ATPase 2 |
|---|---|
| Alternate Symbols: | ATP2B; DAR; DD; DKFZp686P0211; FLJ20293; FLJ38063; MGC45367; SERCA2 |
| PharmGKB Accession Id: | PA71 |
Details
| Cytogenetic Location: | chr12 : q24.11 |
|---|---|
| GP mRNA Boundary†: | chr12 : 109203815 - 109273278 |
| GP Gene Boundary†: | chr12 : 109193815 - 109276278 |
| Strand: | plus |
| Product Name: | ATPase, Ca++ dependent, slow-twitch, cardiac muscle-2, ATPase, Ca++ transporting, cardiac muscle, slow twitch 2, ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 isoform 1, ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 isoform 2, SR Ca(2+)-ATPase 2, calcium pump 2, calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform, endoplasmic reticulum class 1/2 Ca(2+) ATPase, sarcoplasmic/endoplasmic reticulum calcium ATPase 2 |
†
The mRNA boundaries are calculated using the gene's default feature set from NCBI, mapped
onto the UCSC Golden Path. PharmGKB sets gene boundaries by expanding the mRNA boundaries
by no less than 10,000 bases upstream (5') and 3,000 bases downstream (3') to allow for
potential regulatory regions.
Non-Curated Information
A list of non-curated publications that mention this gene along with other genes is available.
PharmGKB Curated Pathways
Curated Information
The following drugs are in curated knowledge about this gene.
| Drug Class | Relationship | Evidence | |
|---|---|---|---|
|
|
antiarrhythmics, class i and iii |
|
Publications, Pathways |
| Drug | Relationship | Evidence | |
|---|---|---|---|
|
|
amiodarone |
|
Pathways |
|
|
arsenic trioxide |
|
Pathways |
|
|
cisapride |
|
Pathways |
|
|
disopyramide |
|
Pathways |
|
|
dofetilide |
|
Pathways |
|
|
droperidol |
|
Pathways |
|
|
flecainide |
|
Pathways |
|
|
halofantrine |
|
Pathways |
|
|
haloperidol |
|
Pathways |
|
|
ibutilide |
|
Pathways |
|
|
lidocaine |
|
Pathways |
|
|
mesoridazine |
|
Pathways |
|
|
methadone |
|
Pathways |
|
|
mexiletine |
|
Pathways |
|
|
pentamidine |
|
Pathways |
|
|
pimozide |
|
Pathways |
|
|
procainamide |
|
Pathways |
|
|
propafenone |
|
Pathways |
|
|
quinidine |
|
Pathways |
|
|
sotalol |
|
Pathways |
|
|
sparfloxacin |
|
Pathways |
|
|
thioridazine |
|
Pathways |
|
|
tocainide |
|
Pathways |
Non-Curated Information
A list of non-curated publications that mention this gene along with other drugs is available.
Non-Curated Information
A list of non-curated publications that mention this gene along with other diseases is available.
LinkOuts
- Ref Seq NT Accession:
- AC_000055
- AC_000144
- NC_000012
- NG_007097
- NT_009775
- NW_001838062
- NW_925395
- UniProtKB Accesssion:
- AT2A2_HUMAN (P16615)
- Ensembl ID:
- ENSG00000174437
- GenAtlas ID:
- ATP2A2
- GeneCard ID:
- ATP2A2
Common Searches
Non-Curated Publications
A list of non-curated publications that mention this gene is available.
