PharmGKB: The Pharmacogenomics Knowledge Base

Gene:
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9

Overview

Alternate Names: ATP-binding cassette, sub-family C, member 9; sulfonylurea receptor 2A
Alternate Symbols: ABC37; ABCC9; CMD1O; FLJ36852; SUR2
PharmGKB Accession Id: PA396

Details

Cytogenetic Location: chr12 : p12.1
GP mRNA Boundary†: chr12 : 21845245 - 21980875
GP Gene Boundary†: chr12 : 21842245 - 21990875
Strand: minus
Product Name: ATP-binding cassette, sub-family C, member 9, ATP-binding cassette, sub-family C, member 9 isoform SUR2A, ATP-binding cassette, sub-family C, member 9 isoform SUR2A-delta-14, ATP-binding cassette, sub-family C, member 9 isoform SUR2B, ATP-binding cassette, sub-family C, member 9, isoform SUR2A, ATP-binding cassette, sub-family C, member 9, isoform SUR2A-delta-14, ATP-binding cassette, sub-family C, member 9, isoform SUR2B, sulfonylurea receptor 2A
† The mRNA boundaries are calculated using the gene's default feature set from NCBI, mapped onto the UCSC Golden Path. PharmGKB sets gene boundaries by expanding the mRNA boundaries by no less than 10,000 bases upstream (5') and 3,000 bases downstream (3') to allow for potential regulatory regions.

Non-Curated Information

A list of non-curated publications that mention this gene along with other genes is available.

PharmGKB Curated Pathways

Curated Information

The following drugs are in curated knowledge about this gene.

  Drug Class Relationship Evidence
No phenotype data No genotype data Literature annotations available Not annotated
antiarrhythmics, class i and iii
  •   
  • PD
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  • FA
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Publications, Pathways
  Drug Relationship Evidence
Phenotype data available Genotype Data Available Literature annotations available Not annotated
amiodarone
  •   
  • PD
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  •   
Pathways
Phenotype data available Genotype Data Available Literature annotations available Not annotated
arsenic trioxide
  •   
  • PD
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  •   
Pathways
Phenotype data available Genotype Data Available Literature annotations available Not annotated
cisapride
  •   
  • PD
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  •   
Pathways
No phenotype data No genotype data Literature annotations available Not annotated
diazoxide
  •   
  •   
  •   
  • FA
  •   
Publications
Phenotype data available Genotype Data Available Literature annotations available Not annotated
disopyramide
  •   
  • PD
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  •   
  •   
Pathways
Phenotype data available Genotype Data Available Literature annotations available Not annotated
dofetilide
  •   
  • PD
  •   
  •   
  •   
Pathways
No phenotype data No genotype data Literature annotations available Not annotated
droperidol
  •   
  • PD
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  •   
  •   
Pathways
No phenotype data No genotype data Literature annotations available Not annotated
flecainide
  •   
  • PD
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  •   
  •   
Pathways
No phenotype data No genotype data Literature annotations available Not annotated
halofantrine
  •   
  • PD
  •   
  •   
  •   
Pathways
Phenotype data available Genotype Data Available Literature annotations available Not annotated
haloperidol
  •   
  • PD
  •   
  •   
  •   
Pathways
No phenotype data No genotype data Literature annotations available Not annotated
ibutilide
  •   
  • PD
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  •   
  •   
Pathways
No phenotype data No genotype data Literature annotations available Not annotated
lidocaine
  •   
  • PD
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  •   
Pathways
No phenotype data No genotype data Literature annotations available Not annotated
mesoridazine
  •   
  • PD
  •   
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  •   
Pathways
No phenotype data No genotype data Literature annotations available Not annotated
methadone
  •   
  • PD
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  •   
Pathways
No phenotype data No genotype data Literature annotations available Not annotated
mexiletine
  •   
  • PD
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  •   
Pathways
No phenotype data No genotype data Literature annotations available Not annotated
pentamidine
  •   
  • PD
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  •   
Pathways
No phenotype data No genotype data Literature annotations available Not annotated
pimozide
  •   
  • PD
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  •   
Pathways
Phenotype data available Genotype Data Available Literature annotations available Not annotated
procainamide
  •   
  • PD
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  •   
  •   
Pathways
No phenotype data No genotype data Literature annotations available Not annotated
propafenone
  •   
  • PD
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  •   
  •   
Pathways
Phenotype data available Genotype Data Available Literature annotations available Not annotated
quinidine
  •   
  • PD
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  •   
  •   
Pathways
Phenotype data available Genotype Data Available Literature annotations available Not annotated
sotalol
  •   
  • PD
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  •   
Pathways
No phenotype data No genotype data Literature annotations available Not annotated
sparfloxacin
  •   
  • PD
  •   
  •   
  •   
Pathways
Phenotype data available No genotype data Literature annotations available Not annotated
thioridazine
  •   
  • PD
  •   
  •   
  •   
Pathways
No phenotype data No genotype data No literature annotations Not annotated
tocainide
  •   
  • PD
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  •   
  •   
Pathways

Non-Curated Information

A list of non-curated publications that mention this gene along with other drugs is available.

Non-Curated Information

A list of non-curated publications that mention this gene along with other diseases is available.

Downloads

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LinkOuts

Entrez Gene ID:
10060
OMIM Accession:
601439
608569
UCSC Genome Browser ID:
NM_005691
Ref Seq NM Accession:
NM_005691
NM_020297
NM_020298
Ref Seq NP Accession:
AAC16057
AAC16058
AAH33804
BAC04300
EAW96452
EAW96453
EAW96454
EAW96455
EAW96456
EAW96457
EAW96458
EAW96459
EAW96460
NP_005682
NP_064693
NP_064694
O60706
Q8N4N7
Q8N9N1
Ref Seq NT Accession:
AC_000055
AC_000144
NC_000012
NT_009714
NW_001838052
NW_925328
UniProtKB Accesssion:
ABCC9_HUMAN (O60706)
Ensembl ID:
ENSG00000069431
GenAtlas ID:
ABCC9
GeneCard ID:
ABCC9
SOURCE ID:
ABCC9
MutDB ID:
ABCC9
PromoLign ID:
ortho_5007
ALFRED ID:
LO001170J
HuGE ID:
ABCC9
Comparative Toxicogenomics Acc ID:
10060
ModBase:
O60706

Common Searches

Non-Curated Publications

A list of non-curated publications that mention this gene is available.

The PharmGKB is financially supported by the NIH/ NIGMS and is managed at Stanford University (U01GM61374).
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