Overview
| Alternate Names: | ATP-BINDING CASSETTE, SUBFAMILY C, MEMBER 5; ABCC5; ATP-binding cassette, sub-family C, member 5; MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 5; MRP5; canalicular multispecific organic anion transporter C |
|---|---|
| Alternate Symbols: | ABC33; ABCC5; AF104942.1; DKFZp686C1782; EST277145; MOAT-C; MOATC; MRP5; SMRP; pABC11 |
| PharmGKB Accession Id: | PA395 |
Details
| Cytogenetic Location: | chr3 : q27.1 |
|---|---|
| GP mRNA Boundary†: | chr3 : 185120416 - 185218421 |
| GP Gene Boundary†: | chr3 : 185117416 - 185228421 |
| Strand: | minus |
| Product Name: | ABCC5 variant 2, ABCC5 variant 3, ABCC5 variant 4, ATP-binding cassette, sub-family C, member 5, ATP-binding cassette, sub-family C, member 5 isoform 1, ATP-binding cassette, sub-family C, member 5 isoform 2, canalicular multispecific organic anion transporter C |
Non-Curated Information
A list of non-curated publications that mention this gene along with other genes is available.
PharmGKB Curated Pathways
Curated Information
The following drugs are in curated knowledge about this gene.
| Drug Class | Relationship | Evidence | |
|---|---|---|---|
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nucleosides and nucleotides excl. reverse transcriptase inhibitors |
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xenobiotics |
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Publications |
| Drug | Relationship | Evidence | |
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cisplatin |
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Publications |
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docetaxel |
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fluorouracil |
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ganciclovir |
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gemcitabine |
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irinotecan |
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mercaptopurine |
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sildenafil |
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thioguanine |
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zidovudine |
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Publications |
Non-Curated Information
A list of non-curated publications that mention this gene along with other drugs is available.
Curated Information
The following diseases are in curated knowledge about this gene.
| Disease | Relationship | Evidence | |
|---|---|---|---|
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Adenocarcinoma |
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Anemia |
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Brain Neoplasms |
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Carcinoma, Non-Small-Cell Lung |
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Colonic Neoplasms |
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Drug Toxicity |
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Heart Failure |
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Leukopenia |
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Lymphoma |
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Melanoma |
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Neutropenia |
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Ovarian Neoplasms |
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Prostatic Neoplasms |
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Publications |
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Thrombocytopenia |
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Publications |
Non-Curated Information
A list of non-curated publications that mention this gene along with other diseases is available.
Curated Phenotype Datasets
These datasets are sorted alphabetically by title.
Downloads
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LinkOuts
- Entrez Gene ID:
- 10057
- OMIM Accession:
- 605251
- UCSC Genome Browser ID:
- NM_005688
- Ref Seq NM Accession:
- NM_001023587
- NM_005688
- Ref Seq NP Accession:
- AAB71758
- AAD04169
- AAD37716
- AAH50744
- AAI40772
- AAI42671
- AAI42720
- AAO49801
- AAW82948
- AAW82949
- AAW82950
- BAA22887
- BAA76608
- BAD92340
- BAD92691
- EAW78306
- EAW78307
- EAW78308
- EAW78309
- EAW78310
- NP_001018881
- NP_005679
- O15440
- Q29ZA9
- Q29ZB1
- Q59FK6
- Q59GK6
- Q86UX3
- Q86W30
- Ref Seq NT Accession:
- AC_000046
- AC_000135
- NC_000003
- NT_005612
- NW_001838884
- NW_921807
- UniProtKB Accesssion:
- MRP5_HUMAN (O15440)
- Ensembl ID:
- ENSG00000114770
- GenAtlas ID:
- ABCC5
- GeneCard ID:
- ABCC5
- SOURCE ID:
- ABCC5
- MutDB ID:
- ABCC5
- PromoLign ID:
- ortho_1429
- ALFRED ID:
- LO010837T
- HuGE ID:
- ABCC5
- Comparative Toxicogenomics Acc ID:
- 10057
- ModBase:
- O15440
Common Searches
Non-Curated Publications
A list of non-curated publications that mention this gene is available.