Overview
| Alternate Names: | (glutamate/neutral; Solute carrier family 1 (glutamate/neutral amino acid transporter),; alanine/serine/cysteine/threonine transporter; glutamate/neutral amino acid transporter; solute carrier family 1, member 4 |
|---|---|
| Alternate Symbols: | ASCT1; SATT |
| PharmGKB Accession Id: | PA35829 |
Details
| Cytogenetic Location: | chr2 : p14 |
|---|---|
| GP mRNA Boundary†: | chr2 : 65070098 - 65104503 |
| GP Gene Boundary†: | chr2 : 65060098 - 65107503 |
| Strand: | plus |
| Product Name: | (glutamate/neutral, acid, alanine/serine/cysteine/threonine transporter, amino, glutamate/neutral amino acid transporter, solute carrier family 1 (glutamate/neutral amino acid transporter), member 4, solute carrier family 1, member 4 |
†
The mRNA boundaries are calculated using the gene's default feature set from NCBI, mapped
onto the UCSC Golden Path. PharmGKB sets gene boundaries by expanding the mRNA boundaries
by no less than 10,000 bases upstream (5') and 3,000 bases downstream (3') to allow for
potential regulatory regions.
Non-Curated Information
A list of non-curated publications that mention this gene along with other genes is available.
Reactome Pathways†
- Amino acid transport across the plasma membrane - (Reactome via Pathway Interaction Database)
- Amino acid uptake across the plasma membrane - (Reactome via Pathway Interaction Database)
†
External pathways not curated by PharmGKB.
Non-Curated Information
A list of non-curated publications that mention this gene along with other drugs is available.
Curated Information
The following diseases are in curated knowledge about this gene.
| Disease | Relationship | Evidence | |
|---|---|---|---|
|
Precursor Cell Lymphoblastic Leukemia-Lymphoma |
|
Publications |
Curated Phenotype Datasets
These datasets are sorted alphabetically by title.
- Treatment-specific changes in gene expression (top 150 discriminating genes)
- FA
Submitted by William Evans, PharmD involving ABCA2, ACAT2, ACTL6A, ALMS1, ANXA2, AP1S2, ARL4C, ATM, AZU1, BAX, BEST1, BMI1, BNIP3L, BPI, BTF3L1, BTF3L3, BYSL, C1R, C8G, CAMP, CBFA2T2, CDKN1B, CENTB2, CEP170, CHD1L, COG2, COMP, CTSG, CUL4B, CYFIP2, CYR61, DEFA1, DEFA3, DYRK1A, E2F5, EIF1AY, ELA2, FAAH, FAM175B, FOS, FZD6, G6PD, GADD45A, GNAS, GP5, GPLD1, GRM5, GSS, HAT1, HHLA1, HOXC6, IGFBP5, IGHG3, IL32, KLF11, LAPTM4B, LCN2, LILRB1, MET, MICA, MICB, MLH1, MPO, MRE11A, MUC3A, MYC, NALCN, NMT2, NR2C1, NR2C2, NRXN2, NTRK3, OLFM4, ORC2L, PBX2, PCM1, PDE6B, PIK3R3, PLS1, PMVK, POLR3C, PRF1, PRKY, PTPRG, RABL3, RALBP1, RBBP8, RBM19, RCC1, RFX4, S100A12, S100A2, S100A4, S100A8, S100A9, SEC22B, SERPING1, SERPINI2, SIM1, SLA, SLC14A2, SLC15A1, SLC1A4, SLC1A7, SMCHD1, SPOCK2, SREBF2, STAG1, STAT1, STK24, STK38, STRAP, TCEAL4, TGIF, THOC2, TOB2, TRA@, TRB@, TXK, TYROBP, UBE2G1, UCHL3, UROS, VARS, YY1, ZBTB1, ZFPL1, ZNF217, ZNF263, mercaptopurine, methotrexate, and Precursor Cell Lymphoblastic Leukemia-Lymphoma
Downloads
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LinkOuts
- Entrez Gene ID:
- 6509
- OMIM Accession:
- 600229
- UCSC Genome Browser ID:
- NM_003038
- Ref Seq NM Accession:
- NM_001135581
- NM_003038
- Ref Seq NP Accession:
- AAA02761
- AAA19438
- AAC51349
- AAF03519
- AAH26216
- AAH72423
- ABM82053
- ABM85232
- BAA94861
- BAD97206
- BAG35883
- BAH12156
- BAH12797
- BAH14357
- EAW99932
- EAW99933
- NP_001129053
- NP_003029
- P43007
- Q53F03
- Q9P2X2
- Ref Seq NT Accession:
- AC_000045
- AC_000134
- NC_000002
- NT_022184
- NW_001838769
- NW_927719
- UniProtKB Accesssion:
- SATT_HUMAN (P43007)
- Ensembl ID:
- ENSG00000115902
- GenAtlas ID:
- SLC1A4
- GeneCard ID:
- SLC1A4
Common Searches
Non-Curated Publications
A list of non-curated publications that mention this gene is available.