PharmGKB: The Pharmacogenomics Knowledge Base

Gene:
KCNJ4
potassium inwardly-rectifying channel, subfamily J, member 4

Overview

Alternate Names: OTTHUMP00000028922; hippocampal inward rectifier potassium channel; inward rectifier K+ channel Kir2.3; potassium inwardly-rectifying channel J4
Alternate Symbols: HIR; HIRK2; HRK1; IRK3; Kir2.3; MGC142066; MGC142068; hIRK2
PharmGKB Accession Id: PA30048

Details

Cytogenetic Location: chr22 : q13.1
GP mRNA Boundary†: chr22 : 37152278 - 37181149
GP Gene Boundary†: chr22 : 37149278 - 37191149
Strand: minus
Product Name: OTTHUMP00000028922, hippocampal inward rectifier potassium channel, inward rectifier K+ channel Kir2.3, potassium inwardly-rectifying channel J4, potassium inwardly-rectifying channel, subfamily J, member 4
† The mRNA boundaries are calculated using the gene's default feature set from NCBI, mapped onto the UCSC Golden Path. PharmGKB sets gene boundaries by expanding the mRNA boundaries by no less than 10,000 bases upstream (5') and 3,000 bases downstream (3') to allow for potential regulatory regions.

Non-Curated Information

A list of non-curated publications that mention this gene along with other genes is available.

PharmGKB Curated Pathways

Curated Information

The following drugs are in curated knowledge about this gene.

  Drug Class Relationship Evidence
No phenotype data No genotype data Literature annotations available Not annotated
antiarrhythmics, class i and iii
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  • FA
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Publications

Non-Curated Information

A list of non-curated publications that mention this gene along with other drugs is available.

Non-Curated Information

A list of non-curated publications that mention this gene along with other diseases is available.

LinkOuts

Entrez Gene ID:
3761
OMIM Accession:
600504
UCSC Genome Browser ID:
NM_004981
Ref Seq NM Accession:
NM_004981
NM_152868
Ref Seq NP Accession:
AAA19962
AAA66076
AAC60632
AAH32562
AAI13507
AAI13509
CAB09790
CAG30393
CAK54537
CAK54836
EAW60235
EAW60236
NP_004972
NP_690607
P48050
Q58F07
Ref Seq NT Accession:
AC_000065
AC_000154
NC_000022
NT_011520
NW_001838745
NW_927628
UniProtKB Accesssion:
IRK4_HUMAN (P48050)
Ensembl ID:
ENSG00000168135
GenAtlas ID:
KCNJ4
GeneCard ID:
KCNJ4
SOURCE ID:
KCNJ4
MutDB ID:
KCNJ4
PromoLign ID:
ortho_8069
HuGE ID:
KCNJ4
ModBase:
P48050
IUPHAR Receptor ID:
Kir2.3 (432)

Common Searches

Non-Curated Publications

A list of non-curated publications that mention this gene is available.

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