PharmGKB: The Pharmacogenomics Knowledge Base

Gene:
KCNE4
potassium voltage-gated channel, Isk-related family, member 4

Overview

Alternate Names: MINK-related peptide 3; cardiac voltage-gated potassium channel accessory subunit 4; minimum potassium ion channel-related peptide 3; potassium voltage-gated channel subfamily E member 4
Alternate Symbols: MGC20353; MIRP3; MiRP3
PharmGKB Accession Id: PA30032

Details

Cytogenetic Location: chr2 : q36.1
GP mRNA Boundary†: chr2 : 223625171 - 223626873
GP Gene Boundary†: chr2 : 223615171 - 223629873
Strand: plus
Product Name: MINK-related peptide 3, cardiac voltage-gated potassium channel accessory subunit 4, minimum potassium ion channel-related peptide 3, potassium voltage-gated channel subfamily E member 4, potassium voltage-gated channel, Isk-related family, member 4
† The mRNA boundaries are calculated using the gene's default feature set from NCBI, mapped onto the UCSC Golden Path. PharmGKB sets gene boundaries by expanding the mRNA boundaries by no less than 10,000 bases upstream (5') and 3,000 bases downstream (3') to allow for potential regulatory regions.

Non-Curated Information

A list of non-curated publications that mention this gene along with other genes is available.

PharmGKB Curated Pathways

Curated Information

The following drugs are in curated knowledge about this gene.

  Drug Class Relationship Evidence
No phenotype data No genotype data Literature annotations available Not annotated
antiarrhythmics, class i and iii
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  • PD
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  • FA
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Publications, Pathways
  Drug Relationship Evidence
Phenotype data available Genotype Data Available Literature annotations available Not annotated
amiodarone
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  • PD
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  •   
Pathways
Phenotype data available Genotype Data Available Literature annotations available Not annotated
arsenic trioxide
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  • PD
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  •   
Pathways
Phenotype data available Genotype Data Available Literature annotations available Not annotated
cisapride
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  • PD
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  •   
Pathways
Phenotype data available Genotype Data Available Literature annotations available Not annotated
disopyramide
  •   
  • PD
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  •   
Pathways
Phenotype data available Genotype Data Available Literature annotations available Not annotated
dofetilide
  •   
  • PD
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  •   
Pathways
No phenotype data No genotype data Literature annotations available Not annotated
droperidol
  •   
  • PD
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  •   
Pathways
No phenotype data No genotype data Literature annotations available Not annotated
flecainide
  •   
  • PD
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  •   
Pathways
No phenotype data No genotype data Literature annotations available Not annotated
halofantrine
  •   
  • PD
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  •   
Pathways
Phenotype data available Genotype Data Available Literature annotations available Not annotated
haloperidol
  •   
  • PD
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  •   
  •   
Pathways
No phenotype data No genotype data Literature annotations available Not annotated
ibutilide
  •   
  • PD
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  •   
Pathways
No phenotype data No genotype data Literature annotations available Not annotated
lidocaine
  •   
  • PD
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  •   
Pathways
No phenotype data No genotype data Literature annotations available Not annotated
mesoridazine
  •   
  • PD
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  •   
Pathways
No phenotype data No genotype data Literature annotations available Not annotated
methadone
  •   
  • PD
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  •   
Pathways
No phenotype data No genotype data Literature annotations available Not annotated
mexiletine
  •   
  • PD
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  •   
Pathways
No phenotype data No genotype data Literature annotations available Not annotated
pentamidine
  •   
  • PD
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  •   
Pathways
No phenotype data No genotype data Literature annotations available Not annotated
pimozide
  •   
  • PD
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  •   
Pathways
Phenotype data available Genotype Data Available Literature annotations available Not annotated
procainamide
  •   
  • PD
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  •   
Pathways
No phenotype data No genotype data Literature annotations available Not annotated
propafenone
  •   
  • PD
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  •   
Pathways
Phenotype data available Genotype Data Available Literature annotations available Not annotated
quinidine
  •   
  • PD
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  •   
Pathways
Phenotype data available Genotype Data Available Literature annotations available Not annotated
sotalol
  •   
  • PD
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  •   
Pathways
No phenotype data No genotype data Literature annotations available Not annotated
sparfloxacin
  •   
  • PD
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  •   
Pathways
Phenotype data available No genotype data Literature annotations available Not annotated
thioridazine
  •   
  • PD
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  •   
Pathways
No phenotype data No genotype data No literature annotations Not annotated
tocainide
  •   
  • PD
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  •   
Pathways

Non-Curated Information

A list of non-curated publications that mention this gene along with other drugs is available.

Non-Curated Information

A list of non-curated publications that mention this gene along with other diseases is available.

Downloads

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LinkOuts

Entrez Gene ID:
23704
OMIM Accession:
607775
UCSC Genome Browser ID:
NM_080671
Ref Seq NM Accession:
NM_080671
Ref Seq NP Accession:
AAH14429
AAL49979
AAX93228
ABB00306
ABM83442
ABQ01241
ABW03499
BAG36019
BAH11761
EAW70810
NP_542402
Q2N1I0
Q8WWG9
Ref Seq NT Accession:
AC_000045
AC_000134
NC_000002
NT_005403
NW_001838865
NW_921618
Ensembl ID:
ENSG00000152049
GenAtlas ID:
KCNE4
GeneCard ID:
KCNE4
SOURCE ID:
KCNE4
MutDB ID:
KCNE4
PromoLign ID:
ortho_1136
HuGE ID:
KCNE4
Comparative Toxicogenomics Acc ID:
23704

Common Searches

Non-Curated Publications

A list of non-curated publications that mention this gene is available.

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