PharmGKB: The Pharmacogenomics Knowledge Base

Gene:
CASQ2
calsequestrin 2 (cardiac muscle)

Overview

Alternate Names: OTTHUMP00000013749; calsequestrin 2, cardiac muscle; calsequestrin 2, fast-twitch, cardiac muscle; cardiac calsequestrin 2
Alternate Symbols: FLJ26321; FLJ93514; PDIB2
PharmGKB Accession Id: PA26096

Details

Cytogenetic Location: chr1 : p13.1
GP mRNA Boundary†: chr1 : 116044166 - 116112793
GP Gene Boundary†: chr1 : 116041166 - 116122793
Strand: minus
Product Name: calsequestrin 2, fast-twitch, cardiac muscle, cardiac calsequestrin 2
† The mRNA boundaries are calculated using the gene's default feature set from NCBI, mapped onto the UCSC Golden Path. PharmGKB sets gene boundaries by expanding the mRNA boundaries by no less than 10,000 bases upstream (5') and 3,000 bases downstream (3') to allow for potential regulatory regions.

PharmGKB Curated Pathways

Curated Information

The following drugs are in curated knowledge about this gene.

  Drug Class Relationship Evidence
No phenotype data No genotype data Literature annotations available Not annotated
antiarrhythmics, class i and iii
  •   
  • PD
  •   
  • FA
  • GN
Publications, Pathways
  Drug Relationship Evidence
Phenotype data available Genotype Data Available Literature annotations available Not annotated
amiodarone
  •   
  • PD
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  •   
  •   
Pathways
Phenotype data available Genotype Data Available Literature annotations available Not annotated
arsenic trioxide
  •   
  • PD
  •   
  •   
  •   
Pathways
Phenotype data available Genotype Data Available Literature annotations available Not annotated
cisapride
  •   
  • PD
  •   
  •   
  •   
Pathways
Phenotype data available Genotype Data Available Literature annotations available Not annotated
disopyramide
  •   
  • PD
  •   
  •   
  •   
Pathways
Phenotype data available Genotype Data Available Literature annotations available Not annotated
dofetilide
  •   
  • PD
  •   
  •   
  •   
Pathways
No phenotype data No genotype data Literature annotations available Not annotated
droperidol
  •   
  • PD
  •   
  •   
  •   
Pathways
No phenotype data No genotype data Literature annotations available Not annotated
flecainide
  •   
  • PD
  •   
  •   
  •   
Pathways
No phenotype data No genotype data Literature annotations available Not annotated
halofantrine
  •   
  • PD
  •   
  •   
  •   
Pathways
Phenotype data available Genotype Data Available Literature annotations available Not annotated
haloperidol
  •   
  • PD
  •   
  •   
  •   
Pathways
No phenotype data No genotype data Literature annotations available Not annotated
ibutilide
  •   
  • PD
  •   
  •   
  •   
Pathways
No phenotype data No genotype data Literature annotations available Not annotated
lidocaine
  •   
  • PD
  •   
  •   
  •   
Pathways
No phenotype data No genotype data Literature annotations available Not annotated
mesoridazine
  •   
  • PD
  •   
  •   
  •   
Pathways
No phenotype data No genotype data Literature annotations available Not annotated
methadone
  •   
  • PD
  •   
  •   
  •   
Pathways
No phenotype data No genotype data Literature annotations available Not annotated
mexiletine
  •   
  • PD
  •   
  •   
  •   
Pathways
No phenotype data No genotype data Literature annotations available Not annotated
pentamidine
  •   
  • PD
  •   
  •   
  •   
Pathways
No phenotype data No genotype data Literature annotations available Not annotated
pimozide
  •   
  • PD
  •   
  •   
  •   
Pathways
Phenotype data available Genotype Data Available Literature annotations available Not annotated
procainamide
  •   
  • PD
  •   
  •   
  •   
Pathways
No phenotype data No genotype data Literature annotations available Not annotated
propafenone
  •   
  • PD
  •   
  •   
  •   
Pathways
Phenotype data available Genotype Data Available Literature annotations available Not annotated
quinidine
  •   
  • PD
  •   
  •   
  •   
Pathways
Phenotype data available Genotype Data Available Literature annotations available Not annotated
sotalol
  •   
  • PD
  •   
  •   
  •   
Pathways
No phenotype data No genotype data Literature annotations available Not annotated
sparfloxacin
  •   
  • PD
  •   
  •   
  •   
Pathways
Phenotype data available No genotype data Literature annotations available Not annotated
thioridazine
  •   
  • PD
  •   
  •   
  •   
Pathways
No phenotype data No genotype data No literature annotations Not annotated
tocainide
  •   
  • PD
  •   
  •   
  •   
Pathways

LinkOuts

Entrez Gene ID:
845
OMIM Accession:
114251
604772
611938
UCSC Genome Browser ID:
NM_001232
Ref Seq NM Accession:
NM_001232
Ref Seq NP Accession:
AAH22288
ABM84145
ABM87547
BAA23494
BAG35873
BAG57061
BAG58422
CAI14532
CAI23373
EAW56635
EAW56636
NP_001223
O14958
Q5T1D2
Ref Seq NT Accession:
AC_000044
AC_000133
NC_000001
NG_008802
NT_019273
NW_001838594
NW_922462
UniProtKB Accesssion:
CASQ2_HUMAN (O14958)
Ensembl ID:
ENSG00000118729
GenAtlas ID:
CASQ2
GeneCard ID:
CASQ2
SOURCE ID:
CASQ2
MutDB ID:
CASQ2
PromoLign ID:
ortho_112
HuGE ID:
CASQ2
Comparative Toxicogenomics Acc ID:
845
ModBase:
O14958

Common Searches

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