PharmGKB: The Pharmacogenomics Knowledge Base

Gene:
ABCC10
ATP-binding cassette, sub-family C (CFTR/MRP), member 10

Overview

Alternate Names: ATP-binding cassette, sub-family C, member 10; multidrug resistance-associated protein 7
Alternate Symbols: EST182763; MRP7; SIMRP7
PharmGKB Accession Id: PA24392

Details

Cytogenetic Location: chr6 : p21.1
GP mRNA Boundary†: chr6 : 43507467 - 43526141
GP Gene Boundary†: chr6 : 43497467 - 43529141
Strand: plus
Product Name: ATP-binding cassette, sub-family C, member 10, multidrug resistance-associated protein 7
† The mRNA boundaries are calculated using the gene's default feature set from NCBI, mapped onto the UCSC Golden Path. PharmGKB sets gene boundaries by expanding the mRNA boundaries by no less than 10,000 bases upstream (5') and 3,000 bases downstream (3') to allow for potential regulatory regions.

PharmGKB Curated Pathways

Curated Information

The following drugs are in curated knowledge about this gene.

  Drug Class Relationship Evidence
No phenotype data No genotype data Literature annotations available Not annotated
vinca alkaloids and analogues
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  • PK
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Pathways
  Drug Relationship Evidence
No phenotype data No genotype data Literature annotations available Not annotated
vinblastine
  •   
  •   
  • PK
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  •   
Pathways
Phenotype data available Genotype Data Available Literature annotations available Not annotated
vincristine
  •   
  •   
  • PK
  •   
  •   
Pathways
No phenotype data No genotype data No literature annotations Not annotated
vindesine
  •   
  •   
  • PK
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  •   
Pathways
No phenotype data No genotype data Literature annotations available Not annotated
vinorelbine
  •   
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  • PK
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Pathways

Curated Information

The following diseases are in curated knowledge about this gene.

  Disease Relationship Evidence
No phenotype data No genotype data Literature annotations available Not annotated
Hodgkin Disease
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  •   
  • PK
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Pathways
No phenotype data No genotype data Literature annotations available Not annotated
Lymphoma, Non-Hodgkin
  •   
  •   
  • PK
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  •   
Pathways
No phenotype data No genotype data Literature annotations available Not annotated
Multiple Myeloma
  •   
  •   
  • PK
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  •   
Pathways
Phenotype data available Genotype Data Available Literature annotations available Not annotated
Precursor Cell Lymphoblastic Leukemia-Lymphoma
  •   
  •   
  • PK
  •   
  •   
Pathways

Downloads

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LinkOuts

Entrez Gene ID:
89845
OMIM Accession:
612509
UCSC Genome Browser ID:
NM_033450
Ref Seq NM Accession:
NM_033450
Ref Seq NP Accession:
AAH24103
AAI66699
AAK39642
BAA92227
BAB15736
CAB59263
CAB63742
CAI23217
CAI23218
CAI23219
CAI23220
EAX04180
EAX04181
EAX04182
EAX04183
EAX04184
EAX04185
NP_258261
Q5T3U2
Q5T3U3
Q5T3U5
Q8TBA1
Q9UFG1
Ref Seq NT Accession:
AC_000049
AC_000138
NC_000006
NT_007592
NW_001838981
NW_923073
UniProtKB Accesssion:
MRP7_HUMAN (Q5T3U5)
Ensembl ID:
ENSG00000124574
GenAtlas ID:
ABCC10
GeneCard ID:
ABCC10
SOURCE ID:
ABCC10
MutDB ID:
ABCC10
HuGE ID:
ABCC10
ModBase:
Q5T3U5

Common Searches

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