Overview
| Alternate Names: | G protein-activated inward rectifier potassium channel 4; cardiac ATP-sensitive potassium channel; cardiac inward rectifier; heart KATP channel; inward rectifier K+ channel KIR3.4; potassium inwardly-rectifying channel J5 |
|---|---|
| Alternate Symbols: | CIR; GIRK4; KATP1; KIR3.4; Kir3.4 |
| PharmGKB Accession Id: | PA216 |
Details
| Cytogenetic Location: | chr11 : q24.3 |
|---|---|
| GP mRNA Boundary†: | chr11 : 128266523 - 128293174 |
| GP Gene Boundary†: | chr11 : 128256523 - 128296174 |
| Strand: | plus |
| Product Name: | G protein-activated inward rectifier potassium channel 4, cardiac ATP-sensitive potassium channel, cardiac inward rectifier, heart KATP channel, inward rectifier K+ channel KIR3.4, potassium inwardly-rectifying channel J5, potassium inwardly-rectifying channel, subfamily J, member 5 |
†
The mRNA boundaries are calculated using the gene's default feature set from NCBI, mapped
onto the UCSC Golden Path. PharmGKB sets gene boundaries by expanding the mRNA boundaries
by no less than 10,000 bases upstream (5') and 3,000 bases downstream (3') to allow for
potential regulatory regions.
Non-Curated Information
A list of non-curated publications that mention this gene along with other genes is available.
PharmGKB Curated Pathways
Curated Information
The following drugs are in curated knowledge about this gene.
Primary phenotype data has been submitted and is available
Primary genotype data has been submitted and is available
| Drug Class | Relationship | Evidence | |
|---|---|---|---|
|
antiarrhythmics, class i and iii |
|
Publications |
Non-Curated Information
A list of non-curated publications that mention this gene along with other drugs is available.
Non-Curated Information
A list of non-curated publications that mention this gene along with other diseases is available.
LinkOuts
- Entrez Gene ID:
- 3762
- OMIM Accession:
- 600734
- UCSC Genome Browser ID:
- NM_000890
- Ref Seq NM Accession:
- NM_000890
- Ref Seq NP Accession:
- AAB07269
- AAB53093
- AAH69386
- AAH69482
- AAH69499
- AAH69571
- AAH74838
- AAH74839
- AAH96834
- BAA08814
- BAG35691
- CAA58565
- EAW67726
- EAW67727
- NP_000881
- P48544
- Q4QRJ2
- Ref Seq NT Accession:
- AC_000054
- AC_000143
- NC_000011
- NT_033899
- NW_001838044
- NW_925173
- UniProtKB Accesssion:
- IRK5_HUMAN (P48544)
- Ensembl ID:
- ENSG00000120457
- GenAtlas ID:
- KCNJ5
- GeneCard ID:
- KCNJ5
- SOURCE ID:
- KCNJ5
- MutDB ID:
- KCNJ5
- PromoLign ID:
- ortho_4726
- HuGE ID:
- KCNJ5
- Comparative Toxicogenomics Acc ID:
- 3762
- ModBase:
- P48544
- IUPHAR Receptor ID:
- Kir3.4 (437)
Common Searches
Non-Curated Publications
A list of non-curated publications that mention this gene is available.