Overview
| Alternate Names: | cardiac inward rectifier potassium channel; inward rectifier K+ channel KIR2.1; inward rectifier potassium channel 2; potassium inwardly-rectifying channel J2 |
|---|---|
| Alternate Symbols: | HHBIRK1; HHIRK1; IRK1; KIR2.1; Kir2.1; LQT7; SQT3 |
| PharmGKB Accession Id: | PA214 |
Details
| Cytogenetic Location: | chr17 : q24.3 |
|---|---|
| GP mRNA Boundary†: | chr17 : 65677271 - 65687780 |
| GP Gene Boundary†: | chr17 : 65667271 - 65690780 |
| Strand: | plus |
| Product Name: | cardiac inward rectifier potassium channel, inward rectifier K+ channel KIR2.1, inward rectifier potassium channel 2, potassium inwardly-rectifying channel J2, potassium inwardly-rectifying channel, subfamily J, member 2 |
†
The mRNA boundaries are calculated using the gene's default feature set from NCBI, mapped
onto the UCSC Golden Path. PharmGKB sets gene boundaries by expanding the mRNA boundaries
by no less than 10,000 bases upstream (5') and 3,000 bases downstream (3') to allow for
potential regulatory regions.
Non-Curated Information
A list of non-curated publications that mention this gene along with other genes is available.
PharmGKB Curated Pathways
Curated Information
The following drugs are in curated knowledge about this gene.
| Drug Class | Relationship | Evidence | |
|---|---|---|---|
|
antiarrhythmics, class i and iii |
|
Publications |
Non-Curated Information
A list of non-curated publications that mention this gene along with other drugs is available.
Curated Information
The following diseases are in curated knowledge about this gene.
| Disease | Relationship | Evidence | |
|---|---|---|---|
|
Atrial Fibrillation |
|
Publications |
Non-Curated Information
A list of non-curated publications that mention this gene along with other diseases is available.
Additional Datasets
These datasets are minimally curated and are sorted alphabetically by title.
LinkOuts
- Entrez Gene ID:
- 3759
- OMIM Accession:
- 170390
- 600681
- 609622
- UCSC Genome Browser ID:
- NM_000891
- Ref Seq NM Accession:
- NM_000891
- Ref Seq NP Accession:
- AAA64282
- AAA91781
- AAB50277
- AAB88797
- AAC39555
- AAC50072
- AAF73241
- AAF73242
- AAI52812
- CAJ33689
- EAW89092
- NP_000882
- P63252
- Ref Seq NT Accession:
- AC_000060
- AC_000149
- NC_000017
- NG_008798
- NT_010641
- NW_001838454
- NW_926918
- UniProtKB Accesssion:
- IRK2_HUMAN (P63252)
- Ensembl ID:
- ENSG00000123700
- GenAtlas ID:
- KCNJ2
- GeneCard ID:
- KCNJ2
- SOURCE ID:
- KCNJ2
- MutDB ID:
- KCNJ2
- PromoLign ID:
- ortho_6708
- HuGE ID:
- KCNJ2
- Comparative Toxicogenomics Acc ID:
- 3759
- ModBase:
- P63252
- IUPHAR Receptor ID:
- Kir2.1 (430)
Common Searches
Non-Curated Publications
A list of non-curated publications that mention this gene is available.