The PharmGKB is a pharmacogenomics knowledge resource that encompasses clinical information including dosing guidelines and drug labels, potentially clinically actionable gene-drug associations and genotype-phenotype relationships. PharmGKB collects, curates and disseminates knowledge about the impact of human genetic variation on drug responses through the following activities:
Russ B. Altman, MD, PhD
Dr. Altman is Professor and Chair of Bioengineering, Professor of Genetics, Medicine, and (by courtesy) Computer Science, and is the principal investigator of the PharmGKB. Dr. Altman has led the PharmGKB since its inception in April 2000. His research interests are in the application of computing technology to basic molecular biological problems of relevance to medicine. He is interested in developing techniques for knowledge-based scientific computation, including novel representations of biological data, particularly for pharmacogenomics. Russ holds an M.D. from Stanford Medical School, a Ph.D. in medical information sciences from Stanford, and an A.B. from Harvard College. He is the current president of the American Society for Clinical Pharmacology and Therapeutics and is certified by the American Board of Internal Medicine.
Russ Altman is a founder, stockholder and a scientific consultant for Personalis Inc.
Teri E. Klein, PhD
Director & Co-Principal Investigator, PharmGKB
Dr. Klein is a Senior Research Scientist in the Department of Genetics and the Director/Co-Principal Investigator for the PharmGKB. She was recruited from the University of California, San Francisco faculty and has been the Director of the PharmGKB since it began in April 2000. Teri received her PhD in medical information sciences from the University of California, San Francisco and a BA in biology/chemistry from the University of California, Santa Cruz. Prior to becoming the director of the PharmGKB in 2000, Dr. Klein was an Associate Adjunct Professor at UCSF.
Michelle Whirl Carrillo, PhD
Assistant Director, PharmGKB
Dr. Carrillo is a Research Scientist in the Department of Genetics and the Assistant Director of the PharmGKB. She joined the PharmGKB as the project's first scientific curator in 2002 after finishing her doctoral work. She briefly left PharmGKB to join the DTC genotyping start-up 23andMe, and returned to the PharmGKB in 2009 as the Assistant Director. Michelle received her PhD in Biophysics from Stanford University and her SB in Biology from MIT.
Blanca S. Pineda, MA
Blanca joined the PharmGKB team in 2010 as the Outreach Coordinator and PharmGKB-PGRN Liaison. Her work focuses on developing and managing the Pharmacogenomics Research Network (PGRN) web site, social networking implementation and outreach coordination. Blanca has been at Stanford University for over twelve years working in administration, management, information technology and education. She has a MA in Interdisciplinary Education with focus in Science, Technology, Environmental Education and Mathematics (Santa Clara University). Blanca is currently attending the University of San Francisco in the Ed.D program in education with a focus in learning and instruction with multimedia.
Tiffany Murray, BA
Administrative Associate/Technical Editor
Tiffany is responsible for coordinating the activities for the PI, Director and Assistant Director as well as providing editorial services for the PharmGKB website since 2001. She has a B.A. from the University of California at San Diego.
Katrin Sangkuhl, PhD
Katrin is a Scientific Curator in the Department of Genetics and has been working for the Pharmacogenomics Knowledgebase (PharmGKB) since 2008. Before joining the PharmGKB team, Katrin was a Postdoctoral Fellow at the Department of Reproductive Biology & Program for Regenerative Medicine, Stanford University. She received her PhD in Biochemistry from the University Leipzig, Germany working in the field of GPCRs and signal transduction. Katrin is a co-chair of the Association for Woman In Science mentoring program at the Stanford University.
Joan M. Hebert, MA
Joan has been a scientific curator for the PharmGKB since 2006. Prior to this, she was a Scientific Database Curator for the Stanford Microarray Database and for the Stanford Microarray Facility. This followed many years of wet lab research at Stanford in the departments of Genetics, Psychiatry and Radiology. Joan holds an M.A. from UC Berkeley in Comparative Biochemistry as well as a B.A. from UC Santa Barbara in Physiology and Cell Biology.
Li Gong, PhD
Li is a research scientist in the Department of Genetics and a scientific curator with PharmGKB. She joined PharmGKB in 2007. Prior to this, Li worked as a senior scientist at Iconix Biosciences Inc. working on microarray data analysis, biomarker discovery and curation for the development of DrugMatrixR toxicogenomics database. She holds a PhD in Molecular Biology and Microbiology from Tufts University School of Medicine, and a BS in Microbiology from Beijing University, P.R. China.
Ellen M. McDonagh, PhD
Ellie came to the PharmGKB in 2011 as a post-doctoral fellow and has now joined the team as a scientific curator. She completed Ph.D in arthritis and immunology research in the Leukocyte Biology Department, Imperial College London, UK. Prior to that, she graduated from Cardiff University, Wales, UK, with a B.Sc. Hons in Genetics, combined with a year’s internship as a Genetic Association Scientist at AstraZeneca, Alderley Edge, UK. She also has experience working in the Tumour Targeting Group, Sheffield University, UK.
Ryan Whaley, BS
Ryan is a software developer in the Department of Genetics and a co-technical lead of the PharmGKB. He is a Java developer with a background in database administration and project management and has been with the PharmGKB since 2007. Ryan received his B.S. in Computer Science and Mathematics at the University of Iowa and then went on to become the database administrator and senior software developer for the Department of Internal Medicine at the University of Iowa Hospitals & Clinics.
Mei Gong, MS
Mei is a research developer with PharmGKB. She joined the PharmGKB in 2004. Mei worked as a staff software engineer in ClearCase Online group with Rational Software Corporation prior to joining PharmGKB. Mei holds a Master's Degree in Computer Science from Northeastern University, China.
Feng Liu, MS
User Interface Engineer
Feng is the user interface designer at PharmGKB having joined the team in 2003. Feng has a MS in computing science & applied psychology from Nottingham University, United Kingdom. Prior to joining the PharmGKB, Feng worked as a user interface designer from the British Geological Survey in London and Rational Software in Cupertino.
Darla Hewett, BS
Darla Hewett is an AI/NLP developer for PharmGKB focusing on knowledge extraction. Darla's research interests are in building semantically-rich models of scientific and business knowledge. She is a founder and frequent contributor to Program for the Future, a special interest group about collective intelligence. She has been on the founding team of five companies and holds several patents in the area of semantic modeling. Darla has a B.S. in Mathematics with a minor in Physics from Washburn University.
Tina Zhou, MSE, MSP
Data Center Director
Tina joined the PharmGKB in 2002 and has served as Datacenter Manager for PharmGKB ever since. Previously, she worked in the management of information systems for private and public sectors for many years. Tina holds an MS in Electrical Engineering and Computer Engineering, an MS in Physics from Marquette University, and a BS in Applied Physics from Shanghai Jiao Tong University, China.
TC Truong, BS
Information Systems Analyst
TC has been involved in IT for PharmGKB since 2002 where he spends most of his time focused on user support and datacenter operations. TC attended UC Davis in biology and a BS in management information systems from San Jose State.
Mark Woon, BSE
Mark is the co-technical lead at PharmGKB and has been with PharmGKB since 2001. He received his BSE in computer science from Princeton University. Prior to working on the PharmGKB project, Mark worked for Sun Microsystems and Netscape Communications.
Julia Barbarino, MSc
Julia is a scientific curator at PharmGKB having completed an MSc in Medical Molecular Genetics at the University of Aberdeen, Scotland. Julia's research focused on epigenetics and human longevity. In addition to her master's degree, she also holds a B.S. in Biochemistry from the University of California, Los Angeles.
Maria Alvarellos, M.S
Prior to becoming a Scientific Curator with PharmGKB in 2014, Maria worked as a science curriculum developer at UC Berkeley with the Lawrence Hall of Science. She received an M.S. in Human Genetics from the University of Michigan, a B.S. in Conservation and Organismal Biology, and a B.A. in Anthropology from San José State University.